Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 11/20 | 0.49 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.49 |
| ▸ | SLC18A2 | Q05940 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12487706 | 0.88 | SIGMAR1 (0.57) | SIGMAR1TAAR1SLC18A2MEN1KMT2A | |
| SCHEMBL16312822 | 0.73 | SIGMAR1 (0.61) | SIGMAR1TAAR1SLC18A2MEN1KMT2A | |
| SCHEMBL19505482 | 0.71 | SIGMAR1 (0.81) | SIGMAR1 | |
| SCHEMBL20627066 | 0.71 | SIGMAR1 (0.49) | SIGMAR1TAAR1SLC18A2MEN1KMT2A | |
| SCHEMBL5832992 | 0.70 | PLA2G1B (0.49) | MEN1KMT2ANPC1RAB9ACYP1A2 | |
| SCHEMBL14604364 | 0.69 | SIGMAR1 (0.65) | SIGMAR1TAAR1SLC18A2MEN1KMT2A | |
| SCHEMBL7986083 | 0.69 | SIGMAR1 (0.65) | SIGMAR1TAAR1SLC18A2MEN1KMT2A | |
| SCHEMBL3379115 | 0.69 | SIGMAR1 (0.65) | SIGMAR1TAAR1SLC18A2MEN1KMT2A | |
| SCHEMBL3379120 | 0.69 | SIGMAR1 (0.65) | SIGMAR1TAAR1SLC18A2MEN1KMT2A | |
| SCHEMBL19505483 | 0.69 | SIGMAR1 (0.82) | SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021050992-A1 | USP30 INHIBITORS AND USES THEREOF | VINCERE BIOSCIENCES, INC. (US) | 2021-03-18 | — | — | WO | disclosed |