Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G1B | P04054 | 1/20 | 0.49 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | KCNH3 | Q9ULD8 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | PTPRZ1 | P23471 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | KDM1A | O60341 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5790558 | 0.86 | IDO1 (0.46) | ALDH1A1KDM4EPTPN1PTPRZ1POLB | |
| SCHEMBL28757043 | 0.81 | HTT (0.53) | ALDH1A1RAB9ASMN1; SMN2KDM4ELMNA | |
| SCHEMBL20246810 | 0.81 | MEN1 (0.58) | ALDH1A1RAB9ASMN1; SMN2KDM4ELMNA | |
| SCHEMBL20246258 | 0.81 | L3MBTL1 (0.45) | ALDH1A1KDM4EPTPN1PTPRZ1KDM1A | |
| SCHEMBL5923870 | 0.78 | GAA (0.50) | ALDH1A1RAB9AKDM4ELMNAMAOB | |
| SCHEMBL21033910 | 0.73 | MEN1 (0.53) | ALDH1A1RAB9ASMN1; SMN2KDM4ELMNA | |
| SCHEMBL1038941 | 0.73 | LMNA (0.65) | PLA2G1BATG4BALDH1A1RAB9AKDM4E | |
| SCHEMBL24590598 | 0.70 | MAPT (0.51) | ALDH1A1RAB9ASMN1; SMN2KDM4EPTPN1 | |
| SCHEMBL17276237 | 0.70 | ALDH1A1 (0.58) | PLA2G1BATG4BALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL23099746 | 0.70 | SIGMAR1 (0.49) | RAB9ANPC1KMT2ACYP1A2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7041851-B2 | Fluorinated phenyl thiophenyl derivatives and their use for imaging serotonin transporters | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2006-05-09 | — | — | US | disclosed |
| US-20030236234-A1 | Fluorinated phenyl thiophenyl derivatives and their use for imaging serotonin transporters | NATIONAL INSTITUTES OF HEALTH-DIRECTOR DEITR | 2003-12-25 | — | — | US | disclosed |
| WO-2003078393-A2 | FLUORINATED PHENYL THIOPHENYL DERIVATIVES AND THEIR USE FOR IMAGING SEROTONIN TRANSPORTERS | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2003-09-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030236234-A1 | Fluorinated phenyl thiophenyl derivatives and their use for imaging serotonin transporters | SLC6A4, SLCO4C1, SLC6A2 | PLA2G1B 3176/4885ATG4B 1503/4885ALDH1A1 2309/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.