Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | HTT | P42858 | 3/20 | 0.35 |
| ▸ | HTR7 | P34969 | 3/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | HTR6 | P50406 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26974931 | 0.98 | KDM4E (0.34) | KDM4EALDH1A1HTTHTR7TDP1 | |
| SCHEMBL20850751 | 0.87 | KDM4E (0.37) | KDM4EALDH1A1HTTHTR7HTR1A | |
| SCHEMBL22963141 | 0.87 | KDM4E (0.37) | KDM4EALDH1A1HTTHTR7HTR1A | |
| SCHEMBL26501022 | 0.85 | PIK3CD (0.39) | KDM4EALDH1A1HTTHTR7HTR1A | |
| SCHEMBL24060966 | 0.85 | ALDH1A1 (0.45) | KDM4EALDH1A1HTTTDP1KMT2A | |
| SCHEMBL25075206 | 0.84 | MAOB (0.38) | KDM4EALDH1A1HTTHTR7HTR2A | |
| SCHEMBL23205212 | 0.83 | HTT (0.35) | KDM4EALDH1A1HTTHTR7HTR1A | |
| SCHEMBL20328741 | 0.82 | ALDH1A1 (0.42) | KDM4EALDH1A1TDP1KMT2A | |
| SCHEMBL26939510 | 0.82 | HTT (0.43) | KDM4EALDH1A1HTTSMN1; SMN2KMT2A | |
| SCHEMBL21401523 | 0.82 | ALDH1A1 (0.39) | ALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021050612-A1 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF RESPIRATORY SYNCYTIAL VIRUS | CIDARA THERAPEUTICS, INC. (US) | 2021-03-18 | — | — | WO | disclosed |