Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 3/20 | 0.39 |
| ▸ | HRH2 | P25021 | 1/20 | 0.36 |
| ▸ | HRH1 | P35367 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.33 |
| ▸ | HTR7 | P34969 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21106253 | 0.87 | HRH2 (0.39) | PIK3CDHRH2HRH1KDM4EALDH1A1 | |
| SCHEMBL22963141 | 0.87 | KDM4E (0.37) | KDM4EALDH1A1HTTHTR7HTR1A | |
| SCHEMBL20850751 | 0.87 | KDM4E (0.37) | KDM4EALDH1A1HTTHTR7HTR1A | |
| SCHEMBL26204334 | 0.86 | HRH2 (0.38) | PIK3CDHRH2HRH1KDM4EALDH1A1 | |
| SCHEMBL23100560 | 0.85 | KDM4E (0.36) | KDM4EALDH1A1HTTHTR7HTR1A | |
| SCHEMBL24060966 | 0.85 | ALDH1A1 (0.45) | KDM4EALDH1A1HTTNPC1RAB9A | |
| SCHEMBL25075206 | 0.84 | MAOB (0.38) | HRH2HRH1KDM4EALDH1A1HTT | |
| SCHEMBL23205212 | 0.83 | HTT (0.35) | HRH2HRH1KDM4EALDH1A1HTT | |
| SCHEMBL26974931 | 0.83 | KDM4E (0.34) | KDM4EALDH1A1HTTHTR7HTR1A | |
| SCHEMBL26939510 | 0.82 | HTT (0.43) | KDM4EALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230321253-A1 | BIFUNCTIONAL COMPOUNDS AND PHARMACEUTICAL USES THEREOF | Risen (Suzhou) Pharma Tech Co., Ltd. (CN) | 2023-10-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230321253-A1 | BIFUNCTIONAL COMPOUNDS AND PHARMACEUTICAL USES THEREOF | KRAS, MDM2, NRAS | PIK3CD 577/4885HRH2 3216/4885HRH1 2655/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.