Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 12/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 12/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 7/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.38 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.38 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.38 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.38 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.38 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8484026 | 0.70 | SRD5A1 (0.50) | CA12CA9MEN1KMT2AHTT | |
| SCHEMBL4020099 | 0.70 | AHR (0.36) | HTTCA2 | |
| SCHEMBL14417477 | 0.69 | KMT2A (0.49) | HDAC1HDAC6MEN1KMT2AHTT | |
| SCHEMBL14417473 | 0.69 | NPC1 (0.55) | HDAC1HDAC6MEN1KMT2AHDAC8 | |
| Hydrochloric Acid SCHEMBL28666905 | 0.69 | AHR (0.38) | HTTCA2ALDH1A1SMN1; SMN2 | |
| SCHEMBL24482978 | 0.69 | CA12 (0.54) | CA12CA9CA2 | |
| SCHEMBL4735384 | 0.68 | SRD5A1 (0.45) | CA12CA9HDAC1HDAC6HDAC8 | |
| SCHEMBL21585537 | 0.67 | CA12 (0.63) | CA12CA9MEN1KMT2AHTT | |
| SCHEMBL5953558 | 0.66 | DRD2 (0.38) | CA12CA9CA2 | |
| SCHEMBL15821065 | 0.65 | HDAC6 (0.44) | CA12CA9HDAC1HDAC6HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10954178-B1 | Synthesis of haloindenes | THE FLORIDA INTERNATIONAL UNIVERSITY BOARD OF TRUSTEES (US) | 2021-03-23 | — | — | US | disclosed |