Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A1 | P18405 | 3/20 | 0.45 |
| ▸ | SRD5A2 | P31213 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | CASP6 | P55212 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.35 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8484026 | 0.90 | SRD5A1 (0.50) | SRD5A1SRD5A2ALDH1A1TP53TSHR | |
| SCHEMBL6756729 | 0.76 | MAOA (0.46) | SRD5A1SRD5A2ALDH1A1TP53TSHR | |
| SCHEMBL5694268 | 0.75 | AKR1B1 (0.39) | SRD5A1SRD5A2ALDH1A1TSHRCA1 | |
| SCHEMBL11459982 | 0.73 | MCHR1 (0.45) | SRD5A1SRD5A2 | |
| SCHEMBL7755721 | 0.73 | ALDH1A1 (0.43) | ALDH1A1TP53SMN1; SMN2 | |
| SCHEMBL24482978 | 0.72 | CA12 (0.54) | SRD5A1SRD5A2CA2CA12CA9 | |
| SCHEMBL6756638 | 0.72 | CA12 (0.45) | SRD5A1SRD5A2ALDH1A1POLBTSHR | |
| SCHEMBL949200 | 0.71 | NOTUM (0.38) | SRD5A1ALDH1A1TDP1TSHRNOTUM | |
| SCHEMBL7616077 | 0.71 | ALDH1A1 (0.42) | SRD5A1SRD5A2ALDH1A1TDP1HSP90AA1 | |
| SCHEMBL8483611 | 0.70 | HDAC3 (0.32) | SRD5A1SRD5A2ALDH1A1HDAC1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008062424-A2 | SUBSTITUTED 4,5-DIHYDRO-1H-PYRAZOLE DERIVATIVES AS CANNABINOID MODULATORS | CADILA HEALTHCARE LIMITED (IN) | 2008-05-29 | — | — | WO | disclosed |