Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 4/20 | 0.38 |
| ▸ | DRD4 | P21917 | 4/20 | 0.38 |
| ▸ | AHR | P35869 | 2/20 | 0.36 |
| ▸ | HTR2A | P28223 | 2/20 | 0.35 |
| ▸ | HTR2C | P28335 | 2/20 | 0.35 |
| ▸ | HTR2B | P41595 | 2/20 | 0.35 |
| ▸ | METAP1 | P53582 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | CA6 | P23280 | 1/20 | 0.33 |
| ▸ | PNMT | P11086 | 1/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | CMA1 | P23946 | 1/20 | 0.32 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5954069 | 0.83 | DRD2 (0.48) | DRD2DRD4AHRHTR2AHTR2C | |
| SCHEMBL13799413 | 0.79 | DRD1 (0.40) | DRD2DRD4 | |
| Hydrochloric Acid SCHEMBL28666905 | 0.78 | AHR (0.38) | DRD2DRD4AHRHTR2AHTR2C | |
| SCHEMBL7776545 | 0.78 | METAP1 (0.37) | METAP1CYP3A4CYP2A6CA12CA9 | |
| SCHEMBL30467249 | 0.78 | METAP1 (0.37) | METAP1CYP3A4CYP2A6CA12CA9 | |
| SCHEMBL2973732 | 0.75 | ALDH1A1 (0.37) | AHRHTR2AHTR2CMETAP1CA1 | |
| SCHEMBL4020099 | 0.75 | AHR (0.36) | DRD2DRD4AHRHTR2AHTR2C | |
| SCHEMBL21694433 | 0.75 | ALDH1A1 (0.42) | CYP3A4 | |
| SCHEMBL5953463 | 0.75 | AHR (0.33) | DRD2DRD4AHRHTR2AHTR2C | |
| SCHEMBL5953678 | 0.75 | MCHR1 (0.33) | DRD2DRD4AHRHTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060052620-A1 | Preparation of substituted indenes | BASELL POLYOLEFINE GMBH (DE) | 2006-03-09 | — | — | US | claimed |
| CN-1653021-A | Preparation of substituted indenes | BASELL POLYOLEFINE GMBH (DE) | 2005-08-10 | — | — | CN | claimed |
| EP-1492749-A1 | PREPARATION OF SUBSTITUTED INDENES | Basell Polyolefine GmbH (DE) | 2005-01-05 | — | — | EP | claimed |
| WO-2003084904-A1 | PREPARATION OF SUBSTITUTED INDENES | BASELL POLYOLEFINE GMBH (DE) | 2003-10-16 | — | — | WO | claimed |
| US-8623407-B2 | Gabapentin-containing solid compositions and process for preparing the same | PFIZER INC. (US) | 2014-01-07 | — | — | US | disclosed |
| US-8623407-B2 | Gabapentin-containing solid compositions and process for preparing the same | PFIZER INC. (US) | 2014-01-07 | — | — | US | disclosed |
| US-20090156677-A1 | Gabapentin-containing Solid Compositions and Process for Preparing the Same | PFIZER INC | 2009-06-18 | — | — | US | disclosed |
| US-20090156677-A1 | Gabapentin-containing Solid Compositions and Process for Preparing the Same | PFIZER INC | 2009-06-18 | — | — | US | disclosed |
| US-7309719-B1 | Storage stability; gabapentin and pregabalin, and neutral alpha -amino acid | WARNER LAMBERT COMPANY, LLC (US) | 2007-12-18 | — | — | US | disclosed |
| US-7309719-B1 | Storage stability; gabapentin and pregabalin, and neutral alpha -amino acid | WARNER LAMBERT COMPANY, LLC (US) | 2007-12-18 | — | — | US | disclosed |
| US-20060052620-A1 | Preparation of substituted indenes | BASELL POLYOLEFINE GMBH (DE) | 2006-03-09 | — | — | US | disclosed |
| CN-1653021-A | Preparation of substituted indenes | BASELL POLYOLEFINE GMBH (DE) | 2005-08-10 | — | — | CN | disclosed |
| EP-1492749-A1 | PREPARATION OF SUBSTITUTED INDENES | Basell Polyolefine GmbH (DE) | 2005-01-05 | — | — | EP | disclosed |
| WO-2003084904-A1 | PREPARATION OF SUBSTITUTED INDENES | BASELL POLYOLEFINE GMBH (DE) | 2003-10-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090156677-A1 | Gabapentin-containing Solid Compositions and Process for Preparing the Same | GABRD, GABRA6, GABRB1 | DRD2 2060/4885DRD4 1653/4885AHR 3196/4885 |
| US-20060052620-A1 | Preparation of substituted indenes | INTS9, CYP1A2, INF2 | DRD2 3715/4885DRD4 2212/4885AHR 140/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.