Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 known ✓ | P08172 | 1/20 | 0.40 |
| ▸ | CHRM1 known ✓ | P11229 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.90 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.90 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.90 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.52 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.52 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.43 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL19856407 | 1.00 | ALDH1A1 (0.90) | ALDH1A1KDM4ETDP1CHRNB2CHRNA4 | |
| Bromide SCHEMBL60491 | 1.00 | ALDH1A1 (0.90) | ALDH1A1KDM4ETDP1CHRNB2CHRNA4 | |
| Bromide SCHEMBL60492 | 0.97 | ALDH1A1 (0.85) | ALDH1A1KDM4ETDP1CHRNB2CHRNA4 | |
| SCHEMBL28168 | 0.97 | ALDH1A1 (0.94) | ALDH1A1KDM4ETDP1CHRNB2CHRNA4 | |
| Hydrogen Sulfide SCHEMBL5998720 | 0.97 | ALDH1A1 (0.94) | ALDH1A1KDM4ETDP1CHRNB2CHRNA4 | |
| SCHEMBL1484108 | 0.97 | ALDH1A1 (0.94) | ALDH1A1KDM4ETDP1CHRNB2CHRNA4 | |
| Bromide SCHEMBL28101098 | 0.95 | ALDH1A1 (0.81) | ALDH1A1KDM4ETDP1CHRNB2CHRNA4 | |
| Bromide SCHEMBL27837346 | 0.95 | ALDH1A1 (0.81) | ALDH1A1KDM4ETDP1CHRNB2CHRNA4 | |
| Iodide SCHEMBL25223891 | 0.94 | ALDH1A1 (0.90) | ALDH1A1KDM4ETDP1CHRNB2CHRNA4 | |
| Iodide SCHEMBL238934 | 0.94 | ALDH1A1 (0.90) | ALDH1A1KDM4ETDP1CHRNB2CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 6112 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119708454-B | Bio-based polylactic acid compatilizer, preparation method thereof and full bio-based polylactic acid composite material | NINGBO INSTITUTE OF MATERIALS TECHNOLOGY & ENGINEERING, CHINESE ACADEMY OF SCIENCES (CN) | 2026-05-26 | — | — | CN | claimed |
| CN-116145156-B | Indoline compound preparation method based on organic electronic synthesis | 六盘水师范学院 | 2026-05-15 | — | — | CN | claimed |
| CN-122025854-A | Aqueous zinc ion battery electrolyte and preparation method and application thereof | 中国科学院长春应用化学研究所 | 2026-05-12 | — | — | CN | claimed |
| US-20260015560-A1 | COMPOSITIONS FOR POST-CMP CLEANING OF MICROELECTRONIC DEVICES | ENTEGRIS INC (US) | 2026-01-15 | — | — | US | claimed |
| US-20250381550-A1 | CARBON DISULFIDE TREATED MATERIALS AND METHODS OF PURIFYING FLUIDS USING THE SAME | ZENITH PURIFICATION LLC (US) | 2025-12-18 | — | — | US | claimed |
| CN-120137232-A | Quaternary ammonium type covalent organic framework doped sulfonated polyether-ether-ketone proton exchange membrane and preparation method thereof | 天津大学 | 2025-06-13 | — | — | CN | claimed |
| CN-120118051-A | Bisphenol AF diglycidyl ether, preparation method thereof, adhesive prepared from bisphenol AF diglycidyl ether and preparation method of adhesive | 山东中柔新材料有限公司 | 2025-06-10 | — | — | CN | claimed |
| CN-111718716-B | Nanostructure with inorganic ligands for electroluminescent devices | 昭荣化学工业株式会社 | 2025-06-10 | — | — | CN | claimed |
| CN-120059155-A | Polysiloxane polycarbonate, transparent flame-retardant scratch-resistant polycarbonate material, and preparation methods and applications thereof | 中国石油化工股份有限公司 | 2025-05-30 | — | — | CN | claimed |
| CN-119874616-B | Organic intermediate and preparation method and application thereof | 四川美域高生物医药科技有限公司 | 2025-05-30 | — | — | CN | claimed |
| US-4849531-A | Process for the preparation of 2,3-epoxyamides | BAYER AKTIENGESELLSCHAFT (DE) | 1989-07-18 | — | — | US | claimed |
| US-4831166-A | REACTING ALKYLENE OXIDE WITH ACYLACETATE USING IONIC HALIDE CATALYST | BASF AKTIENGESELLSCHAFT (DE) | 1989-05-16 | — | — | US | claimed |
| EP-0056356-B1 | A PROCESS TO INDUCE RAPID CURING OF A COPOLYESTER RESIN WITH EPOXIDE COMPOUNDS | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1985-04-24 | — | — | EP | claimed |
| US-4370452-A | Process to induce rapid curing of a copolyester resin with epoxide compounds and a composition formed for that process | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1983-01-25 | — | — | US | claimed |
| EP-0056356-A1 | A process to induce rapid curing of a copolyester resin with epoxide compounds | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1982-07-21 | — | — | EP | claimed |
| US-4112065-A | Compositions of bis(ortho-substituted phenyl)carbodiimides and quaternary ammonium salts and their use thereof in combatting ectoparasitic tick infestations of animals | BAYER AKTIENGESELLSCHAFT (GE) | 1978-09-05 | — | — | US | claimed |
| US-4056547-A | FROM AN ALKALI METAL OR AMMONIUM CYANATE AND A BENZYL CHLORIDE, CATALYST | KAO SOAP CO., LTD. (JA) | 1977-11-01 | — | — | US | claimed |
| US-4012428-A | Method for preparing 3-methyl-2-(4-halogenophenyl)-butyronitrile | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1977-03-15 | — | — | US | claimed |
| US-3959345-A | FROM CYANOACETYLENE AND HYDROGEN CYANIDE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JA) | 1976-05-25 | — | — | US | claimed |
| US-3940319-A | Electrodeposition of bright tin-nickel alloy | NASGLO INTERNATIONAL CORPORATION (US) | 1976-02-24 | — | — | US | claimed |