Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 known ✓ | P08172 | 1/20 | 0.40 |
| ▸ | CHRM1 known ✓ | P11229 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.90 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.90 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.90 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.52 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.52 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.43 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL19856407 | 1.00 | ALDH1A1 (0.90) | ALDH1A1KDM4ETDP1CHRNB2CHRNA4 | |
| Bromide SCHEMBL231096 | 1.00 | ALDH1A1 (0.90) | ALDH1A1KDM4ETDP1CHRNB2CHRNA4 | |
| Bromide SCHEMBL60492 | 0.97 | ALDH1A1 (0.85) | ALDH1A1KDM4ETDP1CHRNB2CHRNA4 | |
| SCHEMBL28168 | 0.97 | ALDH1A1 (0.94) | ALDH1A1KDM4ETDP1CHRNB2CHRNA4 | |
| Hydrogen Sulfide SCHEMBL5998720 | 0.97 | ALDH1A1 (0.94) | ALDH1A1KDM4ETDP1CHRNB2CHRNA4 | |
| SCHEMBL1484108 | 0.97 | ALDH1A1 (0.94) | ALDH1A1KDM4ETDP1CHRNB2CHRNA4 | |
| Bromide SCHEMBL28101098 | 0.95 | ALDH1A1 (0.81) | ALDH1A1KDM4ETDP1CHRNB2CHRNA4 | |
| Bromide SCHEMBL27837346 | 0.95 | ALDH1A1 (0.81) | ALDH1A1KDM4ETDP1CHRNB2CHRNA4 | |
| Iodide SCHEMBL25223891 | 0.94 | ALDH1A1 (0.90) | ALDH1A1KDM4ETDP1CHRNB2CHRNA4 | |
| Iodide SCHEMBL238934 | 0.94 | ALDH1A1 (0.90) | ALDH1A1KDM4ETDP1CHRNB2CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1261 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122071449-A | Substituted biphenyl compounds and application thereof in synthesis of cola pyrroside | 北京凯因格领生物技术有限公司 | 2026-05-22 | — | — | CN | claimed |
| US-20250248296-A1 | DEFECT ENGINEERING IN WIDE BANDGAP PEROVSKITES FOR EFFICIENT AND STABLE FULLY TEXTURED PEROVSKITE-SILICON TANDEM SOLAR CELLS | UNITED STATES DEPARTMENT OF ENERGY | 2025-07-31 | — | — | US | claimed |
| EP-4347668-B1 | PROCESS FOR RECOVERING QUATERNARY SALT BROMINATION CATALYST | DDP SPECIALTY ELECTRONIC MATERIALS US LLC (US) | 2025-04-02 | — | — | EP | claimed |
| CN-119661385-A | Method for connecting dibromo on aniline compound | 上海泰坦科技股份有限公司 | 2025-03-21 | — | — | CN | claimed |
| CN-119638559-A | Multi-site substituted bromopyrene intermediate and derivative, preparation method and application thereof | 广东工业大学 | 2025-03-18 | — | — | CN | claimed |
| CN-119613413-A | Non-azolanet Process for the preparation of tam | 上海皓元医药股份有限公司 | 2025-03-14 | — | — | CN | claimed |
| CN-119080587-A | Halogenated pyrenyl intermediate, derivative thereof, preparation method and application | 广东工业大学 | 2024-12-06 | — | — | CN | claimed |
| CN-114166921-B | Application of chloramine derivatization reagent in double bond position identification | 中国科学院上海有机化学研究所 | 2024-04-26 | — | — | CN | claimed |
| EP-4347668-A1 | PROCESS FOR RECOVERING QUATERNARY SALT BROMINATION CATALYST | DDP Specialty Electronic Materials US, LLC (US) | 2024-04-10 | — | — | EP | claimed |
| CN-117665175-A | Detection method of antioxidant in jet fuel | 中国石油化工股份有限公司 | 2024-03-08 | — | — | CN | claimed |
| US-20060193968-A1 | Method for attachment of biomolecules to medical device surfaces | MEDTRONIC, INC. | 2006-08-31 | — | — | US | claimed |
| US-20060099326-A1 | Method for attachment of biomolecules to medical device surfaces | MEDTRONIC, INC. | 2006-05-11 | — | — | US | claimed |
| US-6773822-B2 | ANTIFUNGAL AGENT MAY BE PRESENT IN THE GYPSUM CORE AND/OR ON ONE OR BOTH OF THE PAPER FACINGS, AND MAY BE ENCAPSULATED IN A MATERIAL THAT RELEASES THE ANTIFUNGAL AGENT OVER TIME AND/OR UPON EXPOSURE TO MOISTURE. | TEMPLE-INLAND FOREST PRODUCTS CORPORATION | 2004-08-10 | — | — | US | claimed |
| US-20040086543-A1 | Method for attachment of biomolecules to medical device surfaces | MEDTRONIC, INC. | 2004-05-06 | — | — | US | claimed |
| EP-1357952-A2 | METHOD FOR COATING MEDICAL DEVICE SURFACES | Medtronic, Inc. (US) | 2003-11-05 | — | — | EP | claimed |
| US-6617142-B2 | Method for attachment of biomolecules to medical device surfaces | MEDTRONIC, INC. | 2003-09-09 | — | — | US | claimed |
| US-20020120333-A1 | Method for coating medical device surfaces | KEOGH JAMES R (US) | 2002-08-29 | — | — | US | claimed |
| WO-2002060505-A2 | METHOD FOR COATING MEDICAL DEVICE SURFACES | MEDTRONIC, INC. (US) | 2002-08-08 | — | — | WO | claimed |
| US-20020001834-A1 | METHOD FOR ATTACHMENT OF BIOMOLECULES TO MEDICAL DEVICE SURFACES | MEDTRONIC, INC. | 2002-01-03 | — | — | US | claimed |
| US-5925552-A | Method for attachment of biomolecules to medical devices surfaces | MEDTRONIC, INC. (US) | 1999-07-20 | — | — | US | claimed |