Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.39 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.39 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | PLA2G7 | Q13093 | 2/20 | 0.36 |
| ▸ | AKT1 | P31749 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.33 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.33 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.33 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.33 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.33 |
| ▸ | ITGAV | P06756 | 1/20 | 0.33 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29662055 | 1.00 | TAS1R3 (0.39) | TAS1R3TAS1R1TAS1R2TP53PLA2G7 | |
| SCHEMBL18447603 | 1.00 | TAS1R3 (0.39) | TAS1R3TAS1R1TAS1R2TP53PLA2G7 | |
| SCHEMBL18447671 | 0.87 | TP53 (0.41) | TAS1R3TAS1R1TAS1R2TP53PLA2G7 | |
| SCHEMBL29662108 | 0.87 | TP53 (0.41) | TAS1R3TAS1R1TAS1R2TP53PLA2G7 | |
| SCHEMBL23111134 | 0.78 | HTT (0.39) | TAS1R3TAS1R1TAS1R2TP53KDM4E | |
| SCHEMBL18447372 | 0.74 | USP30 (0.37) | TAS1R3TAS1R1TAS1R2TP53KDM4E | |
| SCHEMBL29662048 | 0.74 | USP30 (0.37) | TAS1R3TAS1R1TAS1R2TP53KDM4E | |
| SCHEMBL18448057 | 0.74 | KDM4E (0.42) | TAS1R3TAS1R1TAS1R2TP53KDM4E | |
| SCHEMBL29661992 | 0.74 | KDM4E (0.42) | TAS1R3TAS1R1TAS1R2TP53KDM4E | |
| SCHEMBL16799800 | 0.73 | TP53 (0.41) | TP53PLA2G7LMNAKDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3328836-B1 | CYCLIC N-CARBOXAMIDE COMPOUNDS USEFUL AS HERBICIDES | FMC CORP (US) | 2021-03-24 | — | — | EP | disclosed |