Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.36 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.36 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | SMO | Q99835 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | HTR7 | P34969 | 1/20 | 0.35 |
| ▸ | HTR6 | P50406 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29662108 | 0.85 | TP53 (0.41) | TP53LMNARAB9ATAS1R3TAS1R1 | |
| SCHEMBL18447671 | 0.85 | TP53 (0.41) | TP53LMNARAB9ATAS1R3TAS1R1 | |
| SCHEMBL18447603 | 0.78 | TAS1R3 (0.39) | TP53LMNATAS1R3TAS1R1TAS1R2 | |
| SCHEMBL23111133 | 0.78 | TAS1R3 (0.39) | TP53LMNATAS1R3TAS1R1TAS1R2 | |
| SCHEMBL29662055 | 0.78 | TAS1R3 (0.39) | TP53LMNATAS1R3TAS1R1TAS1R2 | |
| SCHEMBL28860321 | 0.68 | KDM4E (0.40) | TP53LMNARAB9ATAS1R3TAS1R1 | |
| SCHEMBL23111135 | 0.67 | KDM4E (0.39) | TP53LMNARAB9ATAS1R3TAS1R1 | |
| SCHEMBL2089517 | 0.62 | KMT2A (0.52) | HTTTP53LMNARAB9AALDH1A1 | |
| SCHEMBL3032005 | 0.61 | TP53 (0.46) | TP53LMNAKDM4EALDH1A1MEN1 | |
| SCHEMBL6185781 | 0.61 | RAB9A (0.53) | HTTTP53LMNARAB9APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3328836-B1 | CYCLIC N-CARBOXAMIDE COMPOUNDS USEFUL AS HERBICIDES | FMC CORP (US) | 2021-03-24 | — | — | EP | disclosed |