Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.37 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.37 |
| ▸ | ITGAV | P06756 | 1/20 | 0.37 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.37 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.37 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.37 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.37 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.37 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KIF11 | P52732 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28860321 | 0.83 | KDM4E (0.40) | KDM4EITGB3ITGB1ITGAVITGA5 | |
| SCHEMBL29662057 | 0.79 | MEN1 (0.39) | KDM4EITGB3ITGB1ITGAVITGA5 | |
| SCHEMBL18446673 | 0.79 | MEN1 (0.39) | KDM4EITGB3ITGB1ITGAVITGA5 | |
| SCHEMBL28773807 | 0.79 | MEN1 (0.39) | KDM4EITGB3ITGB1ITGAVITGA5 | |
| SCHEMBL18447671 | 0.78 | TP53 (0.41) | KDM4EITGB3ITGB1ITGAVITGA5 | |
| SCHEMBL29662108 | 0.78 | TP53 (0.41) | KDM4EITGB3ITGB1ITGAVITGA5 | |
| SCHEMBL18447372 | 0.68 | USP30 (0.37) | KDM4EITGB3ITGB1ITGAVITGA5 | |
| SCHEMBL29662048 | 0.68 | USP30 (0.37) | KDM4EITGB3ITGB1ITGAVITGA5 | |
| SCHEMBL20048487 | 0.67 | ALDH1A1 (0.46) | KDM4ENPC1RAB9ATP53ALDH1A1 | |
| SCHEMBL23111134 | 0.67 | HTT (0.39) | KDM4ETAS1R3TAS1R1TAS1R2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3328836-B1 | CYCLIC N-CARBOXAMIDE COMPOUNDS USEFUL AS HERBICIDES | FMC CORP (US) | 2021-03-24 | — | — | EP | disclosed |