Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 4/20 | 0.37 |
| ▸ | CTSB | P07858 | 1/20 | 0.35 |
| ▸ | CTSS | P25774 | 1/20 | 0.35 |
| ▸ | CTSK | P43235 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.34 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.34 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.34 |
| ▸ | DPP4 | P27487 | 4/20 | 0.33 |
| ▸ | DPP7 | Q9UHL4 | 3/20 | 0.33 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23112570 | 1.00 | CTSL (0.37) | CTSLCTSBCTSSCTSKHDAC3 | |
| SCHEMBL23112571 | 1.00 | CTSL (0.37) | CTSLCTSBCTSSCTSKHDAC3 | |
| SCHEMBL17841446 | 0.89 | GABRB1 (0.37) | CTSLCTSSCTSKHTT | |
| SCHEMBL17841447 | 0.89 | GABRB1 (0.37) | CTSLCTSSCTSKHTT | |
| SCHEMBL17841444 | 0.89 | GABRB1 (0.37) | CTSLCTSSCTSKHTT | |
| SCHEMBL21981041 | 0.84 | HDAC4 (0.40) | CTSLCTSBCTSSCTSKHDAC4 | |
| SCHEMBL21981039 | 0.84 | HDAC4 (0.40) | CTSLCTSBCTSSCTSKHDAC4 | |
| SCHEMBL21981040 | 0.84 | HDAC4 (0.40) | CTSLCTSBCTSSCTSKHDAC4 | |
| SCHEMBL31329156 | 0.84 | HDAC4 (0.40) | CTSLCTSBCTSSCTSKHDAC4 | |
| SCHEMBL23377637 | 0.82 | MAPT (0.40) | CTSLKDM4EALDH1A1HTTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3793559-A1 | SUBSTITUTED DIHYDROPYRAZOLO PYRAZINE CARBOXAMIDE DERIVATIVES | Bayer Aktiengesellschaft (DE) | 2021-03-24 | — | — | EP | disclosed |