Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A1 | O15245 | 1/20 | 0.55 |
| ▸ | PRCP | P42785 | 1/20 | 0.55 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.49 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 4/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23115288 | 1.00 | SLC22A1 (0.55) | SLC22A1PRCPADRB2GRIN2BPOLB | |
| SCHEMBL23135179 | 1.00 | SLC22A1 (0.55) | SLC22A1PRCPADRB2GRIN2BPOLB | |
| SCHEMBL11363948 | 0.88 | SLC22A1 (0.44) | SLC22A1PRCPADRB2GRIN2B | |
| SCHEMBL19427432 | 0.85 | TBXA2R (0.52) | SLC22A1PRCPADRB2GRIN2BKDM1A | |
| SCHEMBL2065898 | 0.85 | DRD2 (0.55) | SLC22A1PRCPADRB2HTR2AHTR2C | |
| SCHEMBL16591499 | 0.85 | PRCP (0.40) | SLC22A1PRCPADRB2KDM1A | |
| SCHEMBL19427420 | 0.85 | DRD2 (0.55) | SLC22A1PRCPADRB2HTR2AHTR2C | |
| SCHEMBL19427382 | 0.85 | PRCP (0.40) | SLC22A1PRCPADRB2KDM1A | |
| Water SCHEMBL9452384 | 0.84 | DRD2 (0.54) | SLC22A1PRCPADRB2HTR2AHTR2C | |
| Oxalic Acid SCHEMBL11370939 | 0.83 | MEN1 (0.44) | SLC22A1PRCPADRB2KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11345941-B2 | Method for preparing (S)-1-benzyl-1,2,3,4,5,6,7,8-octahydroisoquinoline compound | FUDAN UNIVERSITY (CN) | 2022-05-31 | — | — | US | claimed |
| US-20210087595-A1 | METHOD FOR PREPARING (S)-1-BENZYL-1,2,3,4,5,6,7,8-OCTAHYDROISOQUINOLINE COMPOUND | FUDAN UNIVERSITY (CN) | 2021-03-25 | — | — | US | claimed |
| CN-110643650-A | Preparation method of (S) -1-benzyl-1, 2,3,4,5,6,7, 8-octahydroisoquinoline compound | 复旦大学 | 2020-01-03 | — | — | CN | claimed |
| CN-110643650-B | Preparation method of (S) -1-benzyl-1, 2,3,4,5,6,7, 8-octahydroisoquinoline compound | 复旦大学 | 2023-03-07 | — | — | CN | disclosed |
| CN-110643650-B | Preparation method of (S) -1-benzyl-1, 2,3,4,5,6,7, 8-octahydroisoquinoline compound | 复旦大学 | 2023-03-07 | — | — | CN | disclosed |
| US-11345941-B2 | Method for preparing (S)-1-benzyl-1,2,3,4,5,6,7,8-octahydroisoquinoline compound | FUDAN UNIVERSITY (CN) | 2022-05-31 | — | — | US | disclosed |
| US-11345941-B2 | Method for preparing (S)-1-benzyl-1,2,3,4,5,6,7,8-octahydroisoquinoline compound | FUDAN UNIVERSITY (CN) | 2022-05-31 | — | — | US | disclosed |
| US-11345941-B2 | Method for preparing (S)-1-benzyl-1,2,3,4,5,6,7,8-octahydroisoquinoline compound | FUDAN UNIVERSITY (CN) | 2022-05-31 | — | — | US | disclosed |
| US-11345941-B2 | Method for preparing (S)-1-benzyl-1,2,3,4,5,6,7,8-octahydroisoquinoline compound | FUDAN UNIVERSITY (CN) | 2022-05-31 | — | — | US | disclosed |
| US-20210087595-A1 | METHOD FOR PREPARING (S)-1-BENZYL-1,2,3,4,5,6,7,8-OCTAHYDROISOQUINOLINE COMPOUND | FUDAN UNIVERSITY (CN) | 2021-03-25 | — | — | US | disclosed |
| US-20210087595-A1 | METHOD FOR PREPARING (S)-1-BENZYL-1,2,3,4,5,6,7,8-OCTAHYDROISOQUINOLINE COMPOUND | FUDAN UNIVERSITY (CN) | 2021-03-25 | — | — | US | disclosed |
| US-20210087595-A1 | METHOD FOR PREPARING (S)-1-BENZYL-1,2,3,4,5,6,7,8-OCTAHYDROISOQUINOLINE COMPOUND | FUDAN UNIVERSITY (CN) | 2021-03-25 | — | — | US | disclosed |
| US-20210087595-A1 | METHOD FOR PREPARING (S)-1-BENZYL-1,2,3,4,5,6,7,8-OCTAHYDROISOQUINOLINE COMPOUND | FUDAN UNIVERSITY (CN) | 2021-03-25 | — | — | US | disclosed |
| CN-110643650-A | Preparation method of (S) -1-benzyl-1, 2,3,4,5,6,7, 8-octahydroisoquinoline compound | 复旦大学 | 2020-01-03 | — | — | CN | disclosed |
| CN-110643650-A | Preparation method of (S) -1-benzyl-1, 2,3,4,5,6,7, 8-octahydroisoquinoline compound | 复旦大学 | 2020-01-03 | — | — | CN | disclosed |