SCHEMBL23115342

SCHEMBL23115342

CCCCCCCCC(CCCCCC)C(CCCCCBr)CC(=O)O

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR84 Q9NQS5 12/20 0.55
PPARD Q03181 7/20 0.47
LCK P06239 1/20 0.47
ZDHHC20 Q5W0Z9 1/20 0.47
ZDHHC2 Q9UIJ5 1/20 0.47
FFAR1 O14842 3/20 0.44
FFAR4 Q5NUL3 2/20 0.44
MAPT P10636 1/20 0.43
PPARG P37231 6/20 0.41
PPARA Q07869 6/20 0.41
HDAC11 Q96DB2 5/20 0.41
TSHR P16473 4/20 0.41
ALDH1A1 P00352 2/20 0.41
TLR2 O60603 2/20 0.41
TDP1 Q9NUW8 2/20 0.41
FABP4 P15090 2/20 0.41
PTPN1 P18031 2/20 0.41
SLC22A6 Q4U2R8 1/20 0.41
SLC22A8 Q8TCC7 1/20 0.41
MEN1 O00255 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29144173 1.00 GPR84 (0.55) GPR84PPARDLCKZDHHC20ZDHHC2
SCHEMBL5074154 0.91 GPR84 (0.64) GPR84PPARDLCKZDHHC20ZDHHC2
SCHEMBL23115451 0.86 FFAR4 (0.53) GPR84PPARDLCKZDHHC20ZDHHC2
SCHEMBL5878774 0.85 GPR84 (0.58) GPR84PPARDLCKZDHHC20ZDHHC2
SCHEMBL5878935 0.85 GPR84 (0.58) GPR84PPARDLCKZDHHC20ZDHHC2
SCHEMBL5878841 0.83 GPR84 (0.60) GPR84PPARDLCKZDHHC20ZDHHC2
SCHEMBL7081844 0.81 GPR84 (0.58) GPR84PPARDLCKZDHHC20ZDHHC2
SCHEMBL2577773 0.80 GPR84 (0.54) GPR84PPARDFFAR1FFAR4PPARG
SCHEMBL29001299 0.80 GPR84 (0.56) GPR84PPARDLCKZDHHC20ZDHHC2
SCHEMBL25328535 0.79 GPR84 (0.60) GPR84PPARDLCKZDHHC20ZDHHC2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12312293-B2 Branched tail lipid compounds and compositions for intracellular delivery of therapeutic agents MODERNATX, INC. (US) 2025-05-27 US disclosed
US-20230286903-A1 BRANCHED TAIL LIPID COMPOUNDS AND COMPOSITIONS FOR INTRACELLULAR DELIVERY OF THERAPEUTIC AGENTS ARES CAPITAL CORPORATION, AS AGENT 2023-09-14 US disclosed
US-11597698-B2 Branched tail lipid compounds and compositions for intracellular delivery of therapeutic agents MODERNATX, INC. (US) 2023-03-07 US disclosed
CN-114728887-A Branched tail end lipid compounds and compositions for intracellular delivery of therapeutic agents 摩登纳特斯有限公司 2022-07-08 CN disclosed
US-20220106259-A1 BRANCHED TAIL LIPID COMPOUNDS AND COMPOSITIONS FOR INTRACELLULAR DELIVERY OF THERAPEUTIC AGENTS ARES CAPITAL CORPORATION, AS AGENT 2022-04-07 US disclosed
US-11066355-B2 Branched tail lipid compounds and compositions for intracellular delivery of therapeutic agents MODERNATX, INC. (US) 2021-07-20 US disclosed
US-20210087135-A1 BRANCHED TAIL LIPID COMPOUNDS AND COMPOSITIONS FOR INTRACELLULAR DELIVERY OF THERAPEUTIC AGENTS ARES CAPITAL CORPORATION, AS AGENT 2021-03-25 US disclosed
WO-2021055833-A1 BRANCHED TAIL LIPID COMPOUNDS AND COMPOSITIONS FOR INTRACELLULAR DELIVERY OF THERAPEUTIC AGENTS MODERNATX, INC. (US) 2021-03-25 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230286903-A1 BRANCHED TAIL LIPID COMPOUNDS AND COMPOSITIONS FOR INTRACELLULAR DELIVERY OF THERAPEUTIC AGENTS PLTP, LNPK, PLIN3 GPR84 3936/4885PPARD 1881/4885LCK 2146/4885
US-11597698-B2 Branched tail lipid compounds and compositions for intracellular delivery of therapeutic agents PLTP, LNPK, PLIN3 GPR84 3936/4885PPARD 1881/4885LCK 2146/4885
US-12312293-B2 Branched tail lipid compounds and compositions for intracellular delivery of therapeutic agents PLTP, LNPK, PLIN3 GPR84 3936/4885PPARD 1881/4885LCK 2146/4885
US-11066355-B2 Branched tail lipid compounds and compositions for intracellular delivery of therapeutic agents PLTP, LNPK, PLIN3 GPR84 3936/4885PPARD 1881/4885LCK 2146/4885
US-20210087135-A1 BRANCHED TAIL LIPID COMPOUNDS AND COMPOSITIONS FOR INTRACELLULAR DELIVERY OF THERAPEUTIC AGENTS PLTP, LNPK, PLIN3 GPR84 3936/4885PPARD 1881/4885LCK 2146/4885
US-20220106259-A1 BRANCHED TAIL LIPID COMPOUNDS AND COMPOSITIONS FOR INTRACELLULAR DELIVERY OF THERAPEUTIC AGENTS PLTP, LNPK, PLIN3 GPR84 3936/4885PPARD 1881/4885LCK 2146/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.