SCHEMBL23115451

SCHEMBL23115451

CCCCCCCCC(CCCCC)C(CCCCBr)CCC(=O)O

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FFAR4 Q5NUL3 2/20 0.53
FFAR1 O14842 2/20 0.53
GPR84 Q9NQS5 10/20 0.50
PPARD Q03181 8/20 0.50
PPARG P37231 7/20 0.50
PPARA Q07869 7/20 0.50
HDAC11 Q96DB2 5/20 0.50
TSHR P16473 4/20 0.50
PTPN1 P18031 3/20 0.50
ALDH1A1 P00352 2/20 0.50
TLR2 O60603 2/20 0.50
TDP1 Q9NUW8 2/20 0.50
FABP4 P15090 2/20 0.50
SLC22A6 Q4U2R8 1/20 0.50
SLC22A8 Q8TCC7 1/20 0.50
MEN1 O00255 1/20 0.50
ESR1 P03372 1/20 0.50
ALOX15 P16050 1/20 0.50
PDE4A P27815 1/20 0.50
KMT2A Q03164 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21694523 0.89 FFAR4 (0.59) FFAR4FFAR1GPR84PPARDPPARG
SCHEMBL23115342 0.86 GPR84 (0.55) FFAR4FFAR1GPR84PPARDPPARG
SCHEMBL29144173 0.86 GPR84 (0.55) FFAR4FFAR1GPR84PPARDPPARG
SCHEMBL5879026 0.85 FFAR4 (0.56) FFAR4FFAR1GPR84PPARDPPARG
SCHEMBL17007542 0.85 FFAR4 (0.56) FFAR4FFAR1GPR84PPARDPPARG
SCHEMBL11341413 0.83 FFAR4 (0.58) FFAR4FFAR1GPR84PPARDPPARG
SCHEMBL1358545 0.83 FFAR4 (0.74) FFAR4FFAR1GPR84PPARDPPARG
SCHEMBL10448425 0.83 FFAR4 (0.74) FFAR4FFAR1GPR84PPARDPPARG
SCHEMBL23128413 0.83 FFAR4 (0.74) FFAR4FFAR1GPR84PPARDPPARG
SCHEMBL16131158 0.83 FFAR4 (0.74) FFAR4FFAR1GPR84PPARDPPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12312293-B2 Branched tail lipid compounds and compositions for intracellular delivery of therapeutic agents MODERNATX, INC. (US) 2025-05-27 US disclosed
US-20230286903-A1 BRANCHED TAIL LIPID COMPOUNDS AND COMPOSITIONS FOR INTRACELLULAR DELIVERY OF THERAPEUTIC AGENTS ARES CAPITAL CORPORATION, AS AGENT 2023-09-14 US disclosed
US-11597698-B2 Branched tail lipid compounds and compositions for intracellular delivery of therapeutic agents MODERNATX, INC. (US) 2023-03-07 US disclosed
EP-4031524-A1 BRANCHED TAIL LIPID COMPOUNDS AND COMPOSITIONS FOR INTRACELLULAR DELIVERY OF THERAPEUTIC AGENTS ModernaTX, Inc. (US) 2022-07-27 EP disclosed
CN-114728887-A Branched tail end lipid compounds and compositions for intracellular delivery of therapeutic agents 摩登纳特斯有限公司 2022-07-08 CN disclosed
US-20220106259-A1 BRANCHED TAIL LIPID COMPOUNDS AND COMPOSITIONS FOR INTRACELLULAR DELIVERY OF THERAPEUTIC AGENTS ARES CAPITAL CORPORATION, AS AGENT 2022-04-07 US disclosed
US-11066355-B2 Branched tail lipid compounds and compositions for intracellular delivery of therapeutic agents MODERNATX, INC. (US) 2021-07-20 US disclosed
US-20210087135-A1 BRANCHED TAIL LIPID COMPOUNDS AND COMPOSITIONS FOR INTRACELLULAR DELIVERY OF THERAPEUTIC AGENTS ARES CAPITAL CORPORATION, AS AGENT 2021-03-25 US disclosed
WO-2021055833-A1 BRANCHED TAIL LIPID COMPOUNDS AND COMPOSITIONS FOR INTRACELLULAR DELIVERY OF THERAPEUTIC AGENTS MODERNATX, INC. (US) 2021-03-25 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230286903-A1 BRANCHED TAIL LIPID COMPOUNDS AND COMPOSITIONS FOR INTRACELLULAR DELIVERY OF THERAPEUTIC AGENTS PLTP, LNPK, PLIN3 FFAR4 2369/4885FFAR1 2129/4885GPR84 3936/4885
US-11597698-B2 Branched tail lipid compounds and compositions for intracellular delivery of therapeutic agents PLTP, LNPK, PLIN3 FFAR4 2369/4885FFAR1 2129/4885GPR84 3936/4885
US-12312293-B2 Branched tail lipid compounds and compositions for intracellular delivery of therapeutic agents PLTP, LNPK, PLIN3 FFAR4 2369/4885FFAR1 2129/4885GPR84 3936/4885
US-11066355-B2 Branched tail lipid compounds and compositions for intracellular delivery of therapeutic agents PLTP, LNPK, PLIN3 FFAR4 2369/4885FFAR1 2129/4885GPR84 3936/4885
US-20210087135-A1 BRANCHED TAIL LIPID COMPOUNDS AND COMPOSITIONS FOR INTRACELLULAR DELIVERY OF THERAPEUTIC AGENTS PLTP, LNPK, PLIN3 FFAR4 2369/4885FFAR1 2129/4885GPR84 3936/4885
US-20220106259-A1 BRANCHED TAIL LIPID COMPOUNDS AND COMPOSITIONS FOR INTRACELLULAR DELIVERY OF THERAPEUTIC AGENTS PLTP, LNPK, PLIN3 FFAR4 2369/4885FFAR1 2129/4885GPR84 3936/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.