Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 6/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.72 |
| ▸ | MAPT | P10636 | 2/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.63 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.55 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.54 |
| ▸ | IDH2 | P48735 | 3/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.49 |
| ▸ | NAMPT | P43490 | 1/20 | 0.48 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.47 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23119663 | 0.82 | ERAP1 (0.53) | LMNAALDH1A1MAPTKDM4EERAP1 | |
| SCHEMBL23119684 | 0.81 | NPSR1 (0.56) | LMNAALDH1A1MAPTKDM4ESMN1; SMN2 | |
| SCHEMBL4782068 | 0.80 | ALDH1A1 (0.83) | LMNAALDH1A1MAPTKDM4ESMN1; SMN2 | |
| SCHEMBL7568254 | 0.79 | MEN1 (0.57) | LMNANPSR1GAA | |
| SCHEMBL23119377 | 0.79 | NPSR1 (0.56) | LMNAALDH1A1MAPTKDM4ESMN1; SMN2 | |
| SCHEMBL23119613 | 0.79 | NPSR1 (0.52) | LMNAALDH1A1MAPTKDM4ESMN1; SMN2 | |
| SCHEMBL23119610 | 0.78 | NPSR1 (0.55) | LMNAALDH1A1MAPTKDM4ESMN1; SMN2 | |
| SCHEMBL4781525 | 0.78 | ALDH1A1 (1.00) | LMNAALDH1A1MAPTKDM4ESMN1; SMN2 | |
| SCHEMBL29666321 | 0.77 | MEN1 (0.55) | LMNAALDH1A1NPSR1GAA | |
| SCHEMBL18302531 | 0.77 | MEN1 (0.55) | LMNAALDH1A1NPSR1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021047407-A1 | BIARYL COMPOUND, PHARMACEUTICAL COMPOSITION COMPRISING SAME, PREPARATION METHOD THEREFOR, AND USE THEREOF | 四川科伦博泰生物医药股份有限公司 | 2021-03-18 | — | — | WO | disclosed |