SCHEMBL23120249

SCHEMBL23120249

CCS(=O)(=O)c1cc(C2(C#N)CC2)cnc1-c1nc2cc(S(=O)(=NCC(F)(F)F)C(F)(F)F)ccc2o1

nearest known ligand 0.36

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ UTRN P46939 3/20 0.35
▸ CYP1A2 P05177 1/20 0.35
▸ AHR P35869 1/20 0.35
▸ HDAC6 Q9UBN7 1/20 0.35
▸ MAPT P10636 2/20 0.32
▸ MEN1 O00255 1/20 0.32
▸ KMT2A Q03164 1/20 0.32
▸ MAOB P27338 1/20 0.31
▸ SLC47A1 Q96FL8 1/20 0.31
▸ CETP P11597 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30092813 1.00 UTRN (0.35) UTRNCYP1A2AHRHDAC6MAPT
SCHEMBL29748670 0.95 UTRN (0.35) UTRNCYP1A2AHRHDAC6MAPT
SCHEMBL23120226 0.95 UTRN (0.35) UTRNCYP1A2AHRHDAC6MAPT
SCHEMBL29748627 0.93 UTRN (0.36) UTRNCYP1A2AHRHDAC6MAPT
SCHEMBL27139816 0.93 UTRN (0.36) UTRNCYP1A2AHRHDAC6MAPT
SCHEMBL29748678 0.89 UTRN (0.34) UTRNCYP1A2AHRHDAC6MAPT
SCHEMBL23121378 0.89 UTRN (0.34) UTRNCYP1A2AHRHDAC6MAPT
SCHEMBL23120236 0.87 UTRN (0.36) UTRNCYP1A2AHRHDAC6MAPT
SCHEMBL29748749 0.87 UTRN (0.36) UTRNCYP1A2AHRHDAC6MAPT
SCHEMBL23120234 0.82 LMNA (0.35) —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12503461-B2 Pesticidally active heterocyclic derivatives with sulfur and sulfoximine containing substituents SYNGENTA CROP PROTECTION AG (CH) 2025-12-23 — — US claimed
EP-4031544-B1 PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULFUR AND SULFOXIMINE CONTAINING SUBSTITUENTS SYNGENTA CROP PROTECTION AG (CH) 2024-02-28 — — EP claimed
US-20220372026-A1 PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULFUR AND SULFOXIMINE CONTAINING SUBSTITUENTS SYNGENTA CROP PROTECTION AG (CH) 2022-11-24 — — US claimed
WO-2021053110-A1 PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULFUR AND SULFOXIMINE CONTAINING SUBSTITUENTS SYNGENTA CROP PROTECTION AG (CH) 2021-03-25 — — WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220372026-A1 PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULFUR AND SULFOXIMINE CONTAINING SUBSTITUENTS SQOR, TST, DDT UTRN 4435/4885CYP1A2 489/4885AHR 392/4885
US-12503461-B2 Pesticidally active heterocyclic derivatives with sulfur and sulfoximine containing substituents SQOR, TST, DDT UTRN 4435/4885CYP1A2 489/4885AHR 392/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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