Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES | O14684 | 2/20 | 0.59 |
| ▸ | BCHE | P06276 | 9/20 | 0.53 |
| ▸ | MAOB | P27338 | 2/20 | 0.50 |
| ▸ | MAOA | P21397 | 1/20 | 0.50 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.50 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.49 |
| ▸ | LTC4S | Q16873 | 1/20 | 0.49 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.49 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.48 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23120176 | 0.88 | ALOX5 (0.56) | PTGESNR4A2ALOX5FFAR1 | |
| SCHEMBL23120179 | 0.87 | PTGES (0.58) | PTGESALOX5 | |
| SCHEMBL23120539 | 0.84 | PTGES (0.60) | PTGESBCHEMAOBNR4A2ALOX5 | |
| SCHEMBL563333 | 0.82 | REN (0.50) | KDM4EALDH1A1 | |
| SCHEMBL5697480 | 0.78 | BCHE (0.64) | PTGESBCHEMAOBMAOANR4A2 | |
| SCHEMBL23120140 | 0.78 | MC4R (0.50) | PTGESBCHEALOX5 | |
| SCHEMBL18383719 | 0.77 | CYP4F2 (0.64) | BCHEMAOBMAOANR4A2KDM4E | |
| SCHEMBL23120180 | 0.76 | LPAR1 (0.48) | PTGESFFAR1 | |
| SCHEMBL27713598 | 0.76 | CCR6 (0.52) | ALDH1A1 | |
| SCHEMBL30941082 | 0.75 | ALOX5 (0.50) | BCHEMAOBALOX5LTB4RLTB4R2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021053158-A1 | NOVEL HISTONE METHYLTRANSFERASE INHIBITORS | ALBERT-LUDWIGS-UNIVERSITÄT FREIBURG (DE) | 2021-03-25 | — | — | WO | disclosed |