Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAPEPLD | Q6IQ20 | 1/20 | 0.32 |
| ▸ | PRMT5 | O14744 | 3/20 | 0.31 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23120522 | 0.95 | CPB2 (0.31) | NAPEPLDPRMT5WDR77 | |
| SCHEMBL25048314 | 0.89 | CPB2 (0.32) | PRMT5WDR77 | |
| SCHEMBL23120355 | 0.89 | PRMT5 (0.33) | NAPEPLDPRMT5 | |
| SCHEMBL31617932 | 0.85 | NAPEPLD (0.33) | NAPEPLD | |
| SCHEMBL25047411 | 0.85 | HDAC3 (0.31) | PRMT5WDR77 | |
| SCHEMBL23120524 | 0.84 | CPB2 (0.31) | — | |
| SCHEMBL25047480 | 0.83 | LPAR1 (0.33) | PRMT5WDR77 | |
| SCHEMBL23120386 | 0.83 | — | — | |
| SCHEMBL23137086 | 0.82 | — | — | |
| SCHEMBL25048239 | 0.82 | KDM4E (0.31) | PRMT5WDR77 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021053158-A1 | NOVEL HISTONE METHYLTRANSFERASE INHIBITORS | ALBERT-LUDWIGS-UNIVERSITÄT FREIBURG (DE) | 2021-03-25 | — | — | WO | disclosed |