Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.31 |
| ▸ | YAP1 | P46937 | 1/20 | 0.30 |
| ▸ | GHSR | Q92847 | 1/20 | 0.30 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.30 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25048314 | 0.94 | CPB2 (0.32) | PRMT5WDR77 | |
| SCHEMBL23120522 | 0.87 | CPB2 (0.31) | PRMT5WDR77 | |
| SCHEMBL23120354 | 0.85 | NAPEPLD (0.32) | PRMT5WDR77 | |
| SCHEMBL25047765 | 0.79 | PRMT5 (0.33) | PRMT5WDR77 | |
| SCHEMBL23120524 | 0.78 | CPB2 (0.31) | — | |
| SCHEMBL25047420 | 0.78 | PRMT5 (0.34) | PRMT5WDR77 | |
| SCHEMBL25047839 | 0.77 | DOT1L (0.34) | PRMT5WDR77 | |
| SCHEMBL23135872 | 0.77 | NPEPPS (0.33) | PRMT5WDR77 | |
| SCHEMBL31617908 | 0.77 | NNMT (0.34) | — | |
| SCHEMBL23137096 | 0.77 | PRMT5 (0.31) | PRMT5WDR77 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023017152-A1 | SPECIFIC SMALL MOLECULE INHIBITORS THAT BLOCK KMT9 METHYLTRANSFERASE ACTIVITY AND FUNCTION | ALBERT-LUDWIGS-UNIVERSITÄT FREIBURG (DE) | 2023-02-16 | — | — | WO | disclosed |