Chloroxine

Chloroxine

SCHEMBL231205

Oc1c(Cl)cc(Cl)c2cccnc12.[Cu]

nearest known ligand 0.96

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 7/20 0.96
HSP90AA1 P07900 7/20 0.96
MEN1 O00255 6/20 0.96
HTT P42858 6/20 0.96
KMT2A Q03164 6/20 0.96
SMN1; SMN2 Q16637 6/20 0.96
TDP1 Q9NUW8 6/20 0.96
MAPT P10636 5/20 0.96
LMNA P02545 5/20 0.96
ALDH1A1 P00352 4/20 0.96
TP53 P04637 4/20 0.96
MMP14 P50281 3/20 0.96
OPRK1 P41145 3/20 0.96
ALOX15 P16050 3/20 0.96
SLC6A2 P23975 3/20 0.96
CYP3A4 P08684 2/20 0.96
ALOX12 P18054 2/20 0.96
ALOX15B O15296 1/20 0.96
NR1I2 O75469 1/20 0.96
HTR1A P08908 1/20 0.96

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Chloroxine SCHEMBL3350 0.98 KDM4E (1.00) KDM4EHSP90AA1MEN1HTTKMT2A
Chloroxine SCHEMBL29399997 0.98 KDM4E (1.00) KDM4EHSP90AA1MEN1HTTKMT2A
Chloroxine SCHEMBL29389908 0.98 KDM4E (1.00) KDM4EHSP90AA1MEN1HTTKMT2A
Chloroxine SCHEMBL6677225 0.96 KDM4E (0.96) KDM4EHSP90AA1MEN1HTTKMT2A
Chloroxine SCHEMBL22734873 0.96 KDM4E (0.96) KDM4EHSP90AA1MEN1HTTKMT2A
Chloroxine SCHEMBL9135479 0.96 KDM4E (0.96) KDM4EHSP90AA1MEN1HTTKMT2A
Chloroxine SCHEMBL31016232 0.96 KDM4E (0.96) KDM4EHSP90AA1MEN1HTTKMT2A
Chloroxine SCHEMBL4293183 0.96 KDM4E (0.96) KDM4EHSP90AA1MEN1HTTKMT2A
Chloroxine SCHEMBL4297732 0.96 KDM4E (0.96) KDM4EHSP90AA1MEN1HTTKMT2A
Chloroxine SCHEMBL28519932 0.96 KDM4E (0.96) KDM4EHSP90AA1MEN1HTTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9422591-B2 Methods and kits for detecting mastitis RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) 2016-08-23 US disclosed
US-20140206010-A1 METHODS AND KITS FOR DETECTING MASTITIS RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) 2014-07-24 US disclosed
WO-2013016512-A1 METHODS AND KITS FOR DETECTING MASTITIS UNIVERSITY OF MEDICINE AND DENTISTRY OF NEW JERSEY (US) 2013-01-31 WO disclosed
US-8183047-B2 Methods of detecting mastitis by levels of proteasomes UNIVERSITY OF MEDICINE AND DENTISTRY OF NEW JERSEY (US) 2012-05-22 US disclosed
US-20120003662-A1 Methods and Kits for Detecting Mastitis UNIVERSITY OF MEDICINE AND DENTISTRY OF NEW JERSEY (US) 2012-01-05 US disclosed
US-20100210022-A1 Systems for and Methods of Detecting Mastitis RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY 2010-08-19 US disclosed
WO-2009052504-A1 SYSTEMS FOR AND METHODS OF DETECTING MASTITIS UNIVERSITY OF MEDICINE & DENTISTRY OF NEW JERSEY (US) 2009-04-23 WO disclosed