Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.50 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.46 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.42 |
| ▸ | AR | P10275 | 1/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.42 |
| ▸ | IGF1R | P08069 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MMP3 | P08254 | 1/20 | 0.39 |
| ▸ | MMP8 | P22894 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2279467 | 0.81 | HPGD (0.44) | HSP90AB1GABRA1GABRB2SMN1; SMN2HPGD | |
| Bicarbonate SCHEMBL29070802 | 0.80 | HSP90AB1 (0.50) | HSP90AB1GABRA1GABRB2SMN1; SMN2HPGD | |
| SCHEMBL25438707 | 0.80 | HPGD (0.43) | HSP90AB1GABRA1GABRB2SMN1; SMN2HPGD | |
| Pyridine SCHEMBL28584588 | 0.79 | HSP90AB1 (0.45) | HSP90AB1GABRA1GABRB2HPGDTSHR | |
| SCHEMBL2804266 | 0.77 | GAA (0.61) | SMN1; SMN2HPGDTSHRKDM4EHSD17B10 | |
| SCHEMBL1659938 | 0.77 | CYP3A4 (0.48) | HSP90AB1GABRA1GABRB2HPGDTSHR | |
| SCHEMBL460037 | 0.77 | CYP3A4 (0.48) | HSP90AB1GABRA1GABRB2HPGDTSHR | |
| SCHEMBL1659934 | 0.77 | CYP3A4 (0.48) | HSP90AB1GABRA1GABRB2HPGDTSHR | |
| SCHEMBL460038 | 0.77 | CYP3A4 (0.48) | HSP90AB1GABRA1GABRB2HPGDTSHR | |
| SCHEMBL18746282 | 0.77 | CYP3A4 (0.48) | HSP90AB1GABRA1GABRB2HPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114831996-B | Animal feed composition with liver protection effect | 贵阳倍隆生物科技有限公司 | 2023-09-22 | — | — | CN | disclosed |
| CN-116490569-A | Conductive polymer composition | 出光兴产株式会社 | 2023-07-25 | — | — | CN | disclosed |
| CN-112516134-B | Application of hydroxyl-containing compound in preparation of medicines | 上海医药集团股份有限公司 | 2023-06-06 | — | — | CN | disclosed |
| US-20230137943-A1 | PHOTOPROXIMITY PROFILING OF PROTEIN-PROTEIN INTERACTIONS IN CELLS | THE UNIVERSITY OF CHICAGO | 2023-05-04 | — | — | US | disclosed |
| CN-110300514-B | Microbial compositions and methods | 孟山都技术公司 | 2023-04-07 | — | — | CN | disclosed |
| CN-114728970-A | Optical proximity analysis of protein-protein interactions in cells | 芝加哥大学 | 2022-07-08 | — | — | CN | disclosed |
| WO-2021055960-A1 | PHOTOPROXIMITY PROFILING OF PROTEIN-PROTEIN INTERACTIONS IN CELLS | THE UNIVERSITY OF CHICAGO (US) | 2021-03-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230137943-A1 | PHOTOPROXIMITY PROFILING OF PROTEIN-PROTEIN INTERACTIONS IN CELLS | PPIA, S100A4, S100A6 | HSP90AB1 1786/4885GABRA1 3651/4885GABRB2 3671/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.