Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MMP3 | P08254 | 1/20 | 0.43 |
| ▸ | MMP8 | P22894 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.39 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.38 |
| ▸ | AOC2 | O75106 | 5/20 | 0.38 |
| ▸ | MAOA | P21397 | 5/20 | 0.38 |
| ▸ | MAOB | P27338 | 5/20 | 0.38 |
| ▸ | DAO | P14920 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23124236 | 0.81 | HSP90AB1 (0.50) | HPGDTSHRMMP3MMP8SMN1; SMN2 | |
| SCHEMBL25438707 | 0.81 | HPGD (0.43) | HPGDTSHRMMP3MMP8SMN1; SMN2 | |
| SCHEMBL7506591 | 0.79 | MMP3 (0.54) | TSHRMMP3MMP8SMN1; SMN2MEN1 | |
| SCHEMBL8398009 | 0.79 | MMP3 (0.54) | TSHRMMP3MMP8SMN1; SMN2MEN1 | |
| SCHEMBL8398017 | 0.79 | MMP3 (0.54) | TSHRMMP3MMP8SMN1; SMN2MEN1 | |
| SCHEMBL6406067 | 0.78 | HPGD (0.40) | HPGDTSHRMMP3MMP8SMN1; SMN2 | |
| SCHEMBL6412064 | 0.78 | HPGD (0.40) | HPGDTSHRMMP3MMP8SMN1; SMN2 | |
| SCHEMBL5109501 | 0.77 | HPGD (0.64) | HPGDTSHRSMN1; SMN2HSP90AB1NISCH | |
| SCHEMBL1519327 | 0.77 | HPGD (0.64) | HPGDTSHRSMN1; SMN2HSP90AB1NISCH | |
| SCHEMBL5847146 | 0.77 | HPGD (0.64) | HPGDTSHRSMN1; SMN2HSP90AB1NISCH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170296505-A1 | LONG-CHAIN CARBOXYCHROMANOLS AND ANALOGS FOR USE AS ANTI-INFLAMMATORY AGENTS | PURDUE RESEARCH FOUNDATION (US) | 2017-10-19 | — | — | US | disclosed |
| US-9676744-B2 | Long-chain carboxychromanols and analogs for use as anti-inflammatory agents | PURDUE RESEARCH FOUNDATION (US) | 2017-06-13 | — | — | US | disclosed |
| US-20150073044-A1 | LONG-CHAIN CARBOXYCHROMANOLS AND ANALOGS FOR USE AS ANTI-INFLAMMATORY AGENTS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2015-03-12 | — | — | US | disclosed |
| US-8822529-B2 | Long-chain carboxychromanols and analogs for use as anti-inflammatory agents | PURDUE RESEARCH FOUNDATION (US) | 2014-09-02 | — | — | US | disclosed |
| US-20110207808-A1 | LONG-CHAIN CARBOXYCHROMANOLS AND ANALOGS FOR USE AS ANTI-INFLAMMATORY AGENTS | PURDUE RESEARCH FOUNDATION (US) | 2011-08-25 | — | — | US | disclosed |
| WO-2010033687-A1 | LONG-CHAIN CARBOXYCHROMANOLS AND ANALOGS FOR USE AS ANTI-INFLAMMATORY AGENTS | PURDUE RESEARCH FOUNDATION (US) | 2010-03-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110207808-A1 | LONG-CHAIN CARBOXYCHROMANOLS AND ANALOGS FOR USE AS ANTI-INFLAMMATORY AGENTS | ALOX12, ALOX5, ALOX15 | HPGD 25/4885TSHR 4489/4885MMP3 251/4885 |
| US-20150073044-A1 | LONG-CHAIN CARBOXYCHROMANOLS AND ANALOGS FOR USE AS ANTI-INFLAMMATORY AGENTS | ALOX12, ALOX5, PTGS1 | HPGD 24/4885TSHR 4403/4885MMP3 245/4885 |
| US-20170296505-A1 | LONG-CHAIN CARBOXYCHROMANOLS AND ANALOGS FOR USE AS ANTI-INFLAMMATORY AGENTS | ALOX12, ALOX5, PTGS1 | HPGD 24/4885TSHR 4403/4885MMP3 245/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.