Sugi Predict

Sugi Predict / Compounds / SCHEMBL2804266

SCHEMBL2804266

SCHEMBL2804266

O=C1CC(C(=O)O)C(c2ccccc2)O1

nearest known ligand 0.61

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ GAA P10253 3/20 0.61
▸ ALDH1A1 P00352 6/20 0.60
▸ KDM4E B2RXH2 2/20 0.58
▸ USP2 O75604 1/20 0.55
▸ TSHR P16473 1/20 0.55
▸ KMT2A Q03164 1/20 0.53
▸ HSD17B10 Q99714 2/20 0.52
▸ HPGD P15428 1/20 0.52
▸ CYP2C9 P11712 1/20 0.50
▸ CYP2C19 P33261 1/20 0.50
▸ LMNA P02545 2/20 0.46
▸ MAPT P10636 1/20 0.46
▸ SMN1; SMN2 Q16637 1/20 0.45
▸ AKR1C3 P42330 1/20 0.41
▸ AKR1C1 Q04828 1/20 0.41
▸ CTRC Q99895 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14276816 0.86 GAA (0.58) GAAALDH1A1KDM4EUSP2TSHR
SCHEMBL19277786 0.82 USP2 (0.62) GAAALDH1A1KDM4EUSP2TSHR
SCHEMBL28239812 0.79 GAA (0.43) GAAALDH1A1KDM4EUSP2TSHR
SCHEMBL4218169 0.78 GAA (0.46) GAAALDH1A1KDM4EUSP2TSHR
SCHEMBL19834324 0.78 KMT2A (0.42) GAAALDH1A1KDM4EUSP2TSHR
SCHEMBL12330011 0.78 GAA (0.45) GAAALDH1A1KDM4EUSP2TSHR
SCHEMBL9343748 0.78 ALDH1A1 (0.58) GAAALDH1A1KDM4EUSP2TSHR
SCHEMBL23124236 0.77 HSP90AB1 (0.50) GAAALDH1A1KDM4ETSHRKMT2A
SCHEMBL26679383 0.77 GAA (0.50) GAAALDH1A1KDM4EUSP2TSHR
SCHEMBL12444359 0.76 GAA (0.40) GAAALDH1A1KDM4EUSP2TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8968711-B2 Cosmetic or dermatological composition comprising a polymer bearing junction groups, and cosmetic treatment process L'OREAL (FR) 2015-03-03 — — US claimed
US-20100272660-A1 COSMETIC OR PHARMACEUTICAL COMPOSITION COMPRISING A POLYCONDENSATE, THE SAID POLYCONDENSATE AND METHOD OF COSMETIC TREATMENT L'OREAL (FR) 2010-10-28 — — US claimed
US-20100239509-A1 COSMETIC OR DERMATOLOGICAL COMPOSITION COMPRISING A POLYMER BEARING JUNCTION GROUPS, AND COSMETIC TREATMENT PROCESS L'OREAL (FR) 2010-09-23 — — US claimed
CN-111146496-B Polymer electrolyte and lithium ion battery containing same 珠海冠宇电池股份有限公司 2021-07-13 — — CN disclosed
CN-111162313-A Polymer electrolyte and lithium ion battery 珠海冠宇电池有限公司 2020-05-15 — — CN disclosed
CN-111146496-A Polymer electrolyte and lithium ion battery containing same 珠海冠宇电池有限公司 2020-05-12 — — CN disclosed
CN-108440510-A A kind of acid amide fungicides 南京正荣医药化学有限公司 2018-08-24 — — CN disclosed
US-8968711-B2 Cosmetic or dermatological composition comprising a polymer bearing junction groups, and cosmetic treatment process L'OREAL (FR) 2015-03-03 — — US disclosed
US-20100272660-A1 COSMETIC OR PHARMACEUTICAL COMPOSITION COMPRISING A POLYCONDENSATE, THE SAID POLYCONDENSATE AND METHOD OF COSMETIC TREATMENT L'OREAL (FR) 2010-10-28 — — US disclosed
US-20100239509-A1 COSMETIC OR DERMATOLOGICAL COMPOSITION COMPRISING A POLYMER BEARING JUNCTION GROUPS, AND COSMETIC TREATMENT PROCESS L'OREAL (FR) 2010-09-23 — — US disclosed
US-20090028807-A1 COMPOSITION COMPRISING A POLYCONDENSATE, METHOD OF TREATMENT, POLYCONDENSATE, AND METHOD OF PREPARATION L'OREAL (FR) 2009-01-29 — — US disclosed
JP-2003096053-A PRODUCTION METHOD OF OPTICALLY ACTIVE 2-BENZYLSUCCINIC ACID MONOAMIDE KURARAY CO LTD 2003-04-03 — — JP disclosed
JP-2003055295-A METHOD FOR PRODUCING OPTICALLY ACTIVE 2-BENZYLSUCCINIC ACID KURARAY CO LTD 2003-02-26 — — JP disclosed
US-5292768-A Compound effective as cerebral insufficiency improver SUNTORY LIMITED (JP) 1994-03-08 — — US disclosed
US-5288752-A Brain disorders SUNTORY LIMITED (JP) 1994-02-22 — — US disclosed
EP-0322248-B1 COMPOUNDS EFFECTIVE AGAINST CEREBRAL INSUFFICIENCY SUNTORY LIMITED (JP) 1993-08-04 — — EP disclosed
US-5179092-A Cognition activators SUNTORY LIMITED (JP) 1993-01-12 — — US disclosed
US-5057514-A Compounds effective as cerebral schemia treating agents SUNTORY LIMITED (JP) 1991-10-15 — — US disclosed
EP-0322248-A2 Compounds effective against cerebral insufficiency SUNTORY LIMITED (JP) 1989-06-28 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100239509-A1 COSMETIC OR DERMATOLOGICAL COMPOSITION COMPRISING A POLYMER BEARING JUNCTION GROUPS, AND COSMETIC TREATMENT PROCESS CUTA, SUCLG1, KRT18 GAA 342/4885ALDH1A1 1901/4885KDM4E 2504/4885
US-20090028807-A1 COMPOSITION COMPRISING A POLYCONDENSATE, METHOD OF TREATMENT, POLYCONDENSATE, AND METHOD OF PREPARATION CUTA, SYMPK, TPRKB GAA 874/4885ALDH1A1 4765/4885KDM4E 1615/4885
US-20100272660-A1 COSMETIC OR PHARMACEUTICAL COMPOSITION COMPRISING A POLYCONDENSATE, THE SAID POLYCONDENSATE AND METHOD OF COSMETIC TREATMENT ACMSD, CUTA, PCCA GAA 654/4885ALDH1A1 1510/4885KDM4E 1109/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.