Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 7/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | FABP4 | P15090 | 3/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.44 |
| ▸ | PPARG | P37231 | 2/20 | 0.43 |
| ▸ | PPARD | Q03181 | 2/20 | 0.43 |
| ▸ | PPARA | Q07869 | 2/20 | 0.43 |
| ▸ | NQO2 | P16083 | 3/20 | 0.42 |
| ▸ | RAD52 | P43351 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2008376 | 0.82 | HTR6 (0.54) | HTR6POLBL3MBTL1FABP4HDAC1 | |
| SCHEMBL2005448 | 0.79 | HTR6 (0.53) | HTR6POLBL3MBTL1FABP4HDAC1 | |
| SCHEMBL2013274 | 0.79 | FABP4 (0.48) | HTR6POLBL3MBTL1FABP4HDAC1 | |
| SCHEMBL2009721 | 0.77 | HTR6 (0.53) | HTR6POLBL3MBTL1FABP4HDAC1 | |
| SCHEMBL2007979 | 0.76 | NQO2 (0.42) | HTR6NQO2RAD52NQO1HTR1A | |
| SCHEMBL2314057 | 0.75 | FABP4 (0.47) | HTR6L3MBTL1FABP4PPARGNQO2 | |
| SCHEMBL1973097 | 0.72 | HTR6 (0.63) | HTR6POLBL3MBTL1FABP4HDAC1 | |
| SCHEMBL2011566 | 0.72 | CPT1A (0.49) | HTR6POLBFABP4MEN1KMT2A | |
| SCHEMBL1976660 | 0.71 | HTR6 (0.61) | HTR6POLBL3MBTL1FABP4HDAC1 | |
| SCHEMBL31159459 | 0.71 | HTR6 (0.68) | HTR6POLBL3MBTL1FABP4HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2200980-B1 | AMINO ARYLSULFONAMIDE COMPOUNDS AND THEIR USE AS 5-HT6 LIGANDS FIELD OF INVENTION | SUVEN LIFE SCIENCES LTD (IN) | 2011-08-03 | — | — | EP | claimed |