Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 11/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.52 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.52 |
| ▸ | FABP4 | P15090 | 1/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.46 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.46 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.46 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.46 |
| ▸ | PPARG | P37231 | 2/20 | 0.45 |
| ▸ | PPARD | Q03181 | 2/20 | 0.45 |
| ▸ | PPARA | Q07869 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2009721 | 0.95 | HTR6 (0.53) | HTR6POLBL3MBTL1HDAC1HDAC6 | |
| SCHEMBL2005448 | 0.89 | HTR6 (0.53) | HTR6POLBL3MBTL1HDAC1HDAC6 | |
| SCHEMBL2006196 | 0.84 | HTR6 (0.57) | HTR6NQO2HTR1ADRD2HTR1D | |
| SCHEMBL2312698 | 0.82 | HTR6 (0.50) | HTR6POLBL3MBTL1HDAC1HDAC6 | |
| SCHEMBL1974350 | 0.81 | HTR6 (0.55) | HTR6POLBL3MBTL1HDAC1HDAC6 | |
| SCHEMBL1973855 | 0.80 | HTR6 (0.54) | HTR6POLBL3MBTL1HDAC1HDAC6 | |
| SCHEMBL2007388 | 0.80 | HTR6 (0.44) | HTR6PPARGPPARDPPARA | |
| SCHEMBL2006399 | 0.80 | HTR6 (0.56) | HTR6PPARGPPARDPPARAHTR1A | |
| SCHEMBL2001031 | 0.78 | PDE4A (0.47) | HTR6POLBL3MBTL1HDAC1HDAC6 | |
| SCHEMBL2006044 | 0.77 | HTR6 (0.55) | HTR6NQO2HTR1ADRD2HTR1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2200980-B9 | AMINO ARYLSULFONAMIDE COMPOUNDS AND THEIR USE AS 5-HT6 LIGANDS FIELD OF INVENTION | SUVEN LIFE SCIENCES LTD (IN) | 2011-12-28 | — | — | EP | claimed |
| US-7964627-B2 | Amino arylsulfonamide compounds and their use as 5-HT6 ligands | SUVEN LIFE SCIENCES LIMITED (IN) | 2011-06-21 | — | — | US | claimed |
| US-20100216861-A1 | AMINO ARYLSULFONAMIDE COMPOUNDS AND THEIR USE AS 5-HT6 LIGANDS | SUVEN LIFE SCIENCES LIMITED (IN) | 2010-08-26 | — | — | US | claimed |
| EP-2200980-B9 | AMINO ARYLSULFONAMIDE COMPOUNDS AND THEIR USE AS 5-HT6 LIGANDS FIELD OF INVENTION | SUVEN LIFE SCIENCES LTD (IN) | 2011-12-28 | — | — | EP | disclosed |
| EP-2200980-B1 | AMINO ARYLSULFONAMIDE COMPOUNDS AND THEIR USE AS 5-HT6 LIGANDS FIELD OF INVENTION | SUVEN LIFE SCIENCES LTD (IN) | 2011-08-03 | — | — | EP | disclosed |
| US-7964627-B2 | Amino arylsulfonamide compounds and their use as 5-HT6 ligands | SUVEN LIFE SCIENCES LIMITED (IN) | 2011-06-21 | — | — | US | disclosed |
| US-20100216861-A1 | AMINO ARYLSULFONAMIDE COMPOUNDS AND THEIR USE AS 5-HT6 LIGANDS | SUVEN LIFE SCIENCES LIMITED (IN) | 2010-08-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100216861-A1 | AMINO ARYLSULFONAMIDE COMPOUNDS AND THEIR USE AS 5-HT6 LIGANDS | HTR6, HTR5A, HTR1A | HTR6 1/4885POLB 4667/4885L3MBTL1 3618/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.