Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.30 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.30 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.30 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19917469 | 0.83 | CES2 (0.36) | ADRB2CYP3A4HSD17B10ADRA2AADRA2B | |
| SCHEMBL6741548 | 0.81 | PDE2A (0.32) | ADRB2 | |
| SCHEMBL6745375 | 0.81 | PDE2A (0.32) | ADRB2 | |
| SCHEMBL22981828 | 0.77 | — | — | |
| SCHEMBL29707045 | 0.77 | — | — | |
| SCHEMBL6745174 | 0.76 | PDE2A (0.46) | ADRB2CYP3A4HSD17B10ADRA2AADRA2B | |
| SCHEMBL733675 | 0.71 | AHR (0.39) | CYP3A4 | |
| SCHEMBL29710388 | 0.71 | AHR (0.39) | CYP3A4 | |
| SCHEMBL23095908 | 0.70 | PDE2A (0.35) | ADRB2CYP3A4HSD17B10ADRA2AADRA2B | |
| SCHEMBL500009 | 0.70 | APLNR (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3795570-A1 | SUBSTITUTED QUINOLINE-8-CARBONITRILE DERIVATIVES HAVING ANDROGEN RECEPTOR DEGRADATION ACTIVITY AND USES THEREOF | Accutar Biotechnology Inc. (US) | 2021-03-24 | — | — | EP | disclosed |