SCHEMBL733675

SCHEMBL733675

Fc1cc(Br)c(Br)cc1F

nearest known ligand 0.39

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
AHR P35869 2/20 0.39
KDM1A O60341 6/20 0.37
KCNH2 Q12809 4/20 0.37
KDM1B Q8NB78 3/20 0.37
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
CA9 Q16790 1/20 0.33
APEX1 P27695 1/20 0.33
AKR1B1 P15121 1/20 0.31
KDM4E B2RXH2 1/20 0.30
CYP3A4 P08684 1/20 0.30
TSHR P16473 1/20 0.30
TDP1 Q9NUW8 1/20 0.30
HTT P42858 1/20 0.30
GAA P10253 1/20 0.30
MAPT P10636 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29710388 1.00 AHR (0.39) AHRKDM1AKCNH2KDM1BCA1
SCHEMBL28157241 0.85 KDM1A (0.44) AHRKDM1AKCNH2KDM1BCA1
SCHEMBL345490 0.85 KDM1A (0.44) KDM1AKCNH2KDM1BCA1CA2
SCHEMBL29365213 0.85 KDM1A (0.44) KDM1AKCNH2KDM1BCA1CA2
SCHEMBL505780 0.83 KDM1A (0.48) AHRKDM1AKCNH2KDM1BCA1
SCHEMBL13451436 0.82 GPR84 (0.35) AHRCA1CA2CA9
SCHEMBL345437 0.82 KDM1A (0.43) KDM1AKCNH2KDM1BCA1CA2
SCHEMBL734289 0.79 KDM1A (0.32) KDM1AKCNH2KDM1BGAAMAPT
SCHEMBL3753430 0.77 CA1 (0.32) KDM1AKCNH2KDM1BCA1CA2
SCHEMBL3150379 0.77 CA1 (0.32) KDM1AKCNH2KDM1BCA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 174 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12617793-B2 Organic electron transfer mediator and device comprising same I-SENS, INC. (KR) 2026-05-05 US claimed
CN-117659084-A Aromatic amine modified tridentate phosphine coordination copper complex, and preparation method and application thereof 黑龙江大学 2024-03-08 CN claimed
CN-116514649-A Preparation method of 4, 5-difluorophthalic acid 河南省科学院化学研究所有限公司 2023-08-01 CN claimed
US-20230102721-A1 NOVEL ORGANIC ELECTRON TRANSFER MEDIATOR AND DEVICE COMPRISING SAME I-SENS, INC. (KR) 2023-03-30 US claimed
EP-4083043-A1 NOVEL ORGANIC ELECTRON TRANSFER MEDIATOR AND DEVICE COMPRISING SAME I-SENS, INC. (KR) 2022-11-02 EP claimed
CN-114981271-A Novel organic electron transfer mediator and device comprising same 爱-森新株式会社 2022-08-30 CN claimed
CN-112707807-B Preparation method of 4, 5-difluorophthalic acid 苏州当量生物医药有限公司 2022-06-07 CN claimed
EP-3452471-B1 ORGANIC MOLECULES, ESPECIALLY FOR USE IN OPTOELECTRONIC DEVICES CYNORA GMBH (DE) 2021-12-08 EP claimed
CN-109071501-B Organic molecules, in particular for organic opto-electronic devices 辛诺拉有限公司 2021-07-09 CN claimed
WO-2021133144-A1 NOVEL ORGANIC ELECTRON TRANSFER MEDIATOR AND DEVICE COMPRISING SAME 주식회사 아이센스 2021-07-01 WO claimed
CN-112707807-A Preparation method of 4, 5-difluorophthalic acid 苏州金蚕新材料科技有限公司 2021-04-27 CN claimed
CN-108276445-B Thermal excitation delayed fluorescence main body material and preparation and application thereof 黑龙江大学 2020-03-31 CN claimed
EP-3452471-A1 ORGANIC MOLECULES, ESPECIALLY FOR USE IN OPTOELECTRONIC DEVICES CYNORA GMBH (DE) 2019-03-13 EP claimed
US-7173155-B1 Terphenyl dihalide monomers having sulfonate groups and process for preparing the same GWANGJU INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2007-02-06 US claimed
US-12617793-B2 Organic electron transfer mediator and device comprising same I-SENS, INC. (KR) 2026-05-05 US disclosed
US-20260028531-A1 Liquid Crystalline Compounds MERCK PATENT GMBH (DE) 2026-01-29 US disclosed
EP-4685208-A1 LIQUID CRYSTALLINE COMPOUNDS Merck Patent GmbH (DE) 2026-01-28 EP disclosed
US-5739166-A ALKYLSULFONYL OR AMINOSULFONYL SUBSTITUTED AROMATIC COMPOUNDS AS NON-STEROIDAL ANTIINFLAMMATORY AGENT G.D. SEARLE & CO. (US) 1998-04-14 US disclosed
EP-0794942-A1 SUBSTITUTED BIPHENYL COMPOUNDS FOR THE TREATMENT OF INFLAMMATION G.D. SEARLE & CO. (US) 1997-09-17 EP disclosed
WO-1996016934-A1 SUBSTITUTED BIPHENYL COMPOUNDS FOR THE TREATMENT OF INFLAMMATION G.D. SEARLE & CO. (US) 1996-06-06 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12617793-B2 Organic electron transfer mediator and device comprising same SCO2, ETFB, MT-CO1 AHR 1569/4885KDM1A 1721/4885KCNH2 1116/4885
US-20260028531-A1 Liquid Crystalline Compounds POU2F1, FES, POU2F2 AHR 3068/4885KDM1A 3482/4885KCNH2 235/4885
US-20230102721-A1 NOVEL ORGANIC ELECTRON TRANSFER MEDIATOR AND DEVICE COMPRISING SAME MT-ND4, MT-ND2, SLC25A21 AHR 2526/4885KDM1A 1557/4885KCNH2 1463/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.