Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.37 |
| ▸ | MTNR1A | P48039 | 8/20 | 0.37 |
| ▸ | MTNR1B | P49286 | 7/20 | 0.37 |
| ▸ | PDE4A | P27815 | 1/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.32 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.32 |
| ▸ | CAT | P04040 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17347790 | 1.00 | CA12 (0.37) | CA12CA1CA2CA7CA9 | |
| SCHEMBL19228049 | 0.88 | L3MBTL1 (0.34) | MTNR1AMTNR1B | |
| SCHEMBL17347817 | 0.88 | CYP1A2 (0.37) | MTNR1AMTNR1BKMT2A | |
| SCHEMBL23130026 | 0.88 | CYP1A2 (0.37) | MTNR1AMTNR1BKMT2A | |
| SCHEMBL23130216 | 0.87 | MTNR1A (0.40) | CA12CA1CA2CA7CA9 | |
| SCHEMBL17347651 | 0.87 | MTNR1A (0.40) | CA12CA1CA2CA7CA9 | |
| SCHEMBL23130229 | 0.87 | KDM4E (0.33) | CA12CA1CA2CA7CA9 | |
| SCHEMBL17347770 | 0.87 | KDM4E (0.33) | CA12CA1CA2CA7CA9 | |
| SCHEMBL17286499 | 0.85 | CA12 (0.33) | CA12CA1CA2CA7CA9 | |
| SCHEMBL23129929 | 0.85 | MTNR1B (0.42) | CA12CA1CA2CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3154989-B1 | BETA-LACTAMASE INHIBITORS | VENATORX PHARMACEUTICALS INC (US) | 2021-03-24 | — | — | EP | disclosed |