Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23130041 | 0.91 | PARP1 (0.32) | PARP1 | |
| SCHEMBL23130040 | 0.91 | PARP1 (0.32) | PARP1 | |
| SCHEMBL18966608 | 0.90 | MTNR1A (0.34) | — | |
| SCHEMBL17337148 | 0.90 | PRKCB (0.34) | PARP1 | |
| SCHEMBL17337140 | 0.90 | PRKCB (0.34) | PARP1 | |
| SCHEMBL17337191 | 0.88 | TSHR (0.35) | PARP1 | |
| SCHEMBL17337186 | 0.88 | TSHR (0.35) | PARP1 | |
| SCHEMBL18966830 | 0.85 | DRD2 (0.31) | — | |
| SCHEMBL18957034 | 0.84 | NAMPT (0.32) | — | |
| SCHEMBL18966519 | 0.84 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3154989-B1 | BETA-LACTAMASE INHIBITORS | VENATORX PHARMACEUTICALS INC (US) | 2021-03-24 | — | — | EP | disclosed |