Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.34 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.34 |
| ▸ | TRPA1 | O75762 | 4/20 | 0.33 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.32 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17347856 | 1.00 | LMNA (0.37) | LMNAALDH1A1MAPTPRMT5WDR77 | |
| SCHEMBL17337206 | 0.94 | LMNA (0.38) | LMNAALDH1A1TRPA1MTNR1AMTNR1B | |
| SCHEMBL17337203 | 0.94 | LMNA (0.38) | LMNAALDH1A1TRPA1MTNR1AMTNR1B | |
| SCHEMBL17337392 | 0.91 | TSHR (0.35) | ALDH1A1MAPTTSHRPDE4B | |
| SCHEMBL17337390 | 0.91 | TSHR (0.35) | ALDH1A1MAPTTSHRPDE4B | |
| SCHEMBL17349749 | 0.91 | ALDH1A1 (0.40) | ALDH1A1MAPTMTNR1AMTNR1BDRD2 | |
| SCHEMBL23837371 | 0.90 | MAPT (0.32) | MAPT | |
| SCHEMBL17349764 | 0.90 | ALDH1A1 (0.41) | ALDH1A1MTNR1AMTNR1BDRD2 | |
| SCHEMBL17337050 | 0.90 | MAPT (0.35) | ALDH1A1MAPTMTNR1AMTNR1BHTT | |
| SCHEMBL17337109 | 0.90 | MAPT (0.35) | ALDH1A1MAPTMTNR1AMTNR1BHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3154989-B1 | BETA-LACTAMASE INHIBITORS | VENATORX PHARMACEUTICALS INC (US) | 2021-03-24 | — | — | EP | disclosed |