Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | NAMPT | P43490 | 2/20 | 0.38 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 3/20 | 0.36 |
| ▸ | CNR2 | P34972 | 3/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | NAAA | Q02083 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17349749 | 0.97 | ALDH1A1 (0.40) | ALDH1A1ALOX12KMT2ANAMPTMTNR1A | |
| SCHEMBL17337117 | 0.93 | MTNR1A (0.43) | ALDH1A1MTNR1AMTNR1BDRD2 | |
| SCHEMBL17337119 | 0.93 | MTNR1A (0.43) | ALDH1A1MTNR1AMTNR1BDRD2 | |
| SCHEMBL17349774 | 0.92 | NAMPT (0.37) | ALDH1A1NAMPTCNR1CNR2CA12 | |
| SCHEMBL17349999 | 0.91 | NAMPT (0.38) | ALDH1A1NAMPTCNR1CNR2CA12 | |
| SCHEMBL23129898 | 0.90 | LMNA (0.37) | ALDH1A1MTNR1AMTNR1BDRD2 | |
| SCHEMBL17347856 | 0.90 | LMNA (0.37) | ALDH1A1MTNR1AMTNR1BDRD2 | |
| SCHEMBL18966850 | 0.89 | TSHR (0.44) | ALDH1A1KMT2ANAMPTCNR1CNR2 | |
| SCHEMBL17349754 | 0.89 | TSHR (0.36) | ALDH1A1NAMPTMTNR1AMTNR1BCNR2 | |
| SCHEMBL18966596 | 0.88 | ALDH1A1 (0.46) | ALDH1A1NAMPTCNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150361107-A1 | ORALLY BIOAVAILABLE BETA-LACTAMASE INHIBITORS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2015-12-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150361107-A1 | ORALLY BIOAVAILABLE BETA-LACTAMASE INHIBITORS | SI, ALPI, GAA | ALDH1A1 273/4885ALOX12 724/4885KMT2A 1286/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.