Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 7/20 | 0.51 |
| ▸ | MMEL1 | Q495T6 | 5/20 | 0.51 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.42 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2312992 | 1.00 | MME (0.51) | MMEMMEL1FFAR2LMNANPC1 | |
| SCHEMBL2312968 | 0.89 | MME (0.60) | MMEMMEL1FFAR2MEN1KMT2A | |
| SCHEMBL2312962 | 0.89 | MME (0.60) | MMEMMEL1FFAR2MEN1KMT2A | |
| SCHEMBL2315703 | 0.87 | KMT2A (0.53) | MMEMMEL1FFAR2LMNANPC1 | |
| SCHEMBL2315692 | 0.87 | KMT2A (0.53) | MMEMMEL1FFAR2LMNANPC1 | |
| SCHEMBL2318355 | 0.87 | KMT2A (0.58) | MMEMMEL1FFAR2LMNAMEN1 | |
| SCHEMBL2318361 | 0.87 | KMT2A (0.58) | MMEMMEL1FFAR2LMNAMEN1 | |
| SCHEMBL2315641 | 0.84 | MME (0.54) | MMEMMEL1FFAR2LMNAMEN1 | |
| SCHEMBL2315652 | 0.84 | MME (0.54) | MMEMMEL1FFAR2LMNAMEN1 | |
| SCHEMBL2320196 | 0.84 | FFAR2 (0.69) | MMEMMEL1FFAR2LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011092284-A1 | NOVEL AMINO ACID DERIVATIVES AND THEIR USE AS GPR43 RECEPTOR MODULATORS | EUROSCREEN S.A. (BE) | 2011-08-04 | — | — | WO | claimed |