Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.58 |
| ▸ | MEN1 | O00255 | 4/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | HTT | P42858 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | MME | P08473 | 6/20 | 0.58 |
| ▸ | GLA | P06280 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.52 |
| ▸ | MMEL1 | Q495T6 | 3/20 | 0.48 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.47 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.47 |
| ▸ | CNR2 | P34972 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2318361 | 1.00 | KMT2A (0.58) | KMT2AMEN1ALDH1A1HTTMAPT | |
| SCHEMBL2315472 | 0.90 | MEN1 (0.70) | KMT2AMEN1ALDH1A1HTTMAPT | |
| SCHEMBL2315478 | 0.90 | MEN1 (0.70) | KMT2AMEN1ALDH1A1HTTMAPT | |
| SCHEMBL2314965 | 0.89 | MME (0.71) | KMT2AMMEFFAR2MMEL1PSMB8 | |
| SCHEMBL2314959 | 0.89 | MME (0.71) | KMT2AMMEFFAR2MMEL1PSMB8 | |
| SCHEMBL2314735 | 0.88 | MEN1 (0.60) | KMT2AMEN1ALDH1A1MAPTMME | |
| SCHEMBL2314740 | 0.88 | MEN1 (0.60) | KMT2AMEN1ALDH1A1MAPTMME | |
| SCHEMBL2320196 | 0.88 | FFAR2 (0.69) | KMT2AMEN1ALDH1A1HTTMAPT | |
| SCHEMBL2317674 | 0.88 | FFAR2 (0.69) | KMT2AMEN1ALDH1A1HTTMAPT | |
| SCHEMBL2317669 | 0.88 | FFAR2 (0.69) | KMT2AMEN1ALDH1A1HTTMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011092284-A1 | NOVEL AMINO ACID DERIVATIVES AND THEIR USE AS GPR43 RECEPTOR MODULATORS | EUROSCREEN S.A. (BE) | 2011-08-04 | — | — | WO | claimed |