Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 2/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | F2R | P25116 | 1/20 | 0.30 |
| ▸ | CAT | P04040 | 1/20 | 0.30 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17347656 | 1.00 | MTNR1A (0.36) | MTNR1AMTNR1BCA12CA1CA2 | |
| SCHEMBL17347789 | 0.91 | MTNR1A (0.33) | MTNR1AMTNR1BCA12CA1CA2 | |
| SCHEMBL23130023 | 0.91 | MTNR1A (0.33) | MTNR1AMTNR1BCA12CA1CA2 | |
| SCHEMBL17347939 | 0.90 | — | — | |
| SCHEMBL23130177 | 0.89 | ALOX5 (0.37) | MTNR1AMTNR1BCA12CA1CA2 | |
| SCHEMBL17347806 | 0.89 | ALOX5 (0.37) | MTNR1AMTNR1BCA12CA1CA2 | |
| SCHEMBL23129930 | 0.88 | CA12 (0.38) | MTNR1AMTNR1BCA12CA1CA2 | |
| SCHEMBL17347663 | 0.88 | CA12 (0.38) | MTNR1AMTNR1BCA12CA1CA2 | |
| SCHEMBL17347652 | 0.87 | CAT (0.44) | MTNR1AMTNR1BCA12CA1CA2 | |
| SCHEMBL17347653 | 0.86 | MTNR1A (0.33) | MTNR1AMTNR1BCA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3154989-B1 | BETA-LACTAMASE INHIBITORS | VENATORX PHARMACEUTICALS INC (US) | 2021-03-24 | — | — | EP | disclosed |