Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 6/20 | 0.37 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.34 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17347806 | 1.00 | ALOX5 (0.37) | ALOX5MTNR1AMTNR1BMAPTMAPK1 | |
| SCHEMBL23130166 | 0.92 | ALOX5 (0.36) | ALOX5MAPTMAPK1HTTPOLB | |
| SCHEMBL17347832 | 0.92 | ALOX5 (0.36) | ALOX5MAPTMAPK1HTTPOLB | |
| SCHEMBL23130037 | 0.89 | CA12 (0.39) | ALOX5MTNR1AMTNR1BMAPTLMNA | |
| SCHEMBL17347836 | 0.89 | CA12 (0.39) | ALOX5MTNR1AMTNR1BMAPTLMNA | |
| SCHEMBL23130232 | 0.89 | MTNR1A (0.36) | MTNR1AMTNR1BMAPK1HTTLMNA | |
| SCHEMBL17347656 | 0.89 | MTNR1A (0.36) | MTNR1AMTNR1BMAPK1HTTLMNA | |
| SCHEMBL17347744 | 0.89 | ALOX5 (0.36) | ALOX5MAPTMAPK1HTTPOLB | |
| SCHEMBL23129690 | 0.89 | ALOX5 (0.36) | ALOX5MAPTMAPK1HTTPOLB | |
| SCHEMBL17347788 | 0.88 | MTNR1A (0.32) | MTNR1AMTNR1BPOLBCA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3154989-B1 | BETA-LACTAMASE INHIBITORS | VENATORX PHARMACEUTICALS INC (US) | 2021-03-24 | — | — | EP | disclosed |