Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 2/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | TP53 | P04637 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17347697 | 1.00 | MTNR1A (0.36) | MTNR1AMTNR1BMAPTTP53KMT2A | |
| SCHEMBL23129947 | 0.92 | RAB9A (0.36) | MTNR1AMTNR1BMAPTTP53KMT2A | |
| SCHEMBL17347781 | 0.92 | RAB9A (0.36) | MTNR1AMTNR1BMAPTTP53KMT2A | |
| SCHEMBL23130037 | 0.89 | CA12 (0.39) | MTNR1AMTNR1BMAPTKMT2ALMNA | |
| SCHEMBL17347836 | 0.89 | CA12 (0.39) | MTNR1AMTNR1BMAPTKMT2ALMNA | |
| SCHEMBL23130009 | 0.89 | HTT (0.35) | MAPTTP53KMT2ALMNAALOX5 | |
| SCHEMBL17347652 | 0.89 | CAT (0.44) | MTNR1AMTNR1BCA12CA1CA2 | |
| SCHEMBL17347748 | 0.89 | HTT (0.35) | MAPTTP53KMT2ALMNAALOX5 | |
| SCHEMBL17347688 | 0.88 | MTNR1A (0.34) | MTNR1AMTNR1BCA12CA1CA2 | |
| SCHEMBL23129893 | 0.88 | MTNR1A (0.34) | MTNR1AMTNR1BCA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3154989-B1 | BETA-LACTAMASE INHIBITORS | VENATORX PHARMACEUTICALS INC (US) | 2021-03-24 | — | — | EP | disclosed |