Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR2 | O15552 | 1/20 | 0.62 |
| ▸ | MMEL1 | Q495T6 | 8/20 | 0.54 |
| ▸ | MME | P08473 | 4/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.44 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2313157 | 1.00 | FFAR2 (0.62) | FFAR2MMEL1MMELMNAHPGD | |
| SCHEMBL2312968 | 0.89 | MME (0.60) | FFAR2MMEL1MMEL3MBTL1ERCC1 | |
| SCHEMBL2312962 | 0.89 | MME (0.60) | FFAR2MMEL1MMEL3MBTL1ERCC1 | |
| SCHEMBL2313273 | 0.88 | FFAR2 (0.77) | FFAR2MMEL1MMEHPGDALDH1A1 | |
| SCHEMBL2313265 | 0.88 | FFAR2 (0.77) | FFAR2MMEL1MMEHPGDALDH1A1 | |
| SCHEMBL2315245 | 0.84 | FFAR2 (0.79) | FFAR2MMEL1MME | |
| SCHEMBL2315341 | 0.84 | FFAR2 (0.79) | FFAR2MMEL1MME | |
| SCHEMBL2315240 | 0.84 | FFAR2 (0.79) | FFAR2MMEL1MME | |
| SCHEMBL2315954 | 0.84 | FFAR2 (0.60) | FFAR2MMEL1MME | |
| SCHEMBL2315961 | 0.84 | FFAR2 (0.60) | FFAR2MMEL1MME |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011092284-A1 | NOVEL AMINO ACID DERIVATIVES AND THEIR USE AS GPR43 RECEPTOR MODULATORS | EUROSCREEN S.A. (BE) | 2011-08-04 | — | — | WO | claimed |