SCHEMBL23133

SCHEMBL23133

COc1ccc2ncsc2c1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 5/20 0.57
RAB9A P51151 5/20 0.57
MEN1 O00255 4/20 0.57
KMT2A Q03164 4/20 0.57
ALDH1A1 P00352 6/20 0.56
KDM4E B2RXH2 5/20 0.56
SMN1; SMN2 Q16637 3/20 0.56
TDP1 Q9NUW8 2/20 0.56
HPGD P15428 1/20 0.56
CYP1A2 P05177 1/20 0.50
CYP3A4 P08684 1/20 0.50
CYP2C19 P33261 1/20 0.50
L3MBTL1 Q9Y468 2/20 0.49
PDK1 Q15118 1/20 0.49
HKDC1 Q2TB90 1/20 0.47
PKM P14618 1/20 0.46
PFKFB3 Q16875 2/20 0.46
HSD17B10 Q99714 1/20 0.45
DYRK1A Q13627 1/20 0.45
MMP12 P39900 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bromide SCHEMBL1193036 0.98 NPC1 (0.56) NPC1RAB9AMEN1KMT2AALDH1A1
Toluene SCHEMBL11239856 0.89 ALDH1A1 (0.49) NPC1RAB9AMEN1KMT2AALDH1A1
SCHEMBL29992983 0.86 NPC1 (0.56) NPC1RAB9AMEN1KMT2AALDH1A1
Pyrazole SCHEMBL360175 0.85 NPC1 (0.49) NPC1RAB9AMEN1KMT2AALDH1A1
SCHEMBL928266 0.85 NPC1 (0.47) NPC1RAB9AMEN1KMT2AALDH1A1
SCHEMBL29967146 0.85 NPC1 (0.47) NPC1RAB9AMEN1KMT2AALDH1A1
SCHEMBL11719234 0.83 RIPK2 (0.47) NPC1RAB9AMEN1KMT2AALDH1A1
SCHEMBL6032519 0.82 RAB9A (0.46) NPC1RAB9AMEN1KMT2AALDH1A1
SCHEMBL6835755 0.82 MEN1 (0.49) NPC1RAB9AMEN1KMT2AALDH1A1
SCHEMBL4160781 0.81 ALDH1A1 (0.60) NPC1RAB9AMEN1KMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1117 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4441112-A1 METHOD OF UNDERWATER BONDING Henkel AG & Co. KGaA (DE) 2024-10-09 EP claimed
US-20240318052-A1 METHOD OF UNDERWATER BONDING HENKEL AG & CO KGAA (DE) 2024-09-26 US claimed
CN-118355041-A Method for underwater bonding 汉高股份有限及两合公司 2024-07-16 CN claimed
CN-117069676-B 6-Methoxybenzothiazole compound and preparation method and application thereof 北京中医药大学 2024-06-18 CN claimed
WO-2024103023-A2 12-LIPOXYGENASE INHIBITORS FOR THE TREATMENT OF LUPUS VERALOX THERAPEUTICS (US) 2024-05-16 WO claimed
WO-2024097846-A1 ORAL PHARMACEUTICAL FORMULATIONS CONTAINING 4-((2-HYDROXY-3-METHOXYBENZYL)AMINO) BENZENESULFONAMIDE DERIVATIVES VERALOX THERAPEUTICS (US) 2024-05-10 WO claimed
CN-116655847-B Preparation method of temperature-sensitive macromolecular dye, mascara containing temperature-sensitive macromolecular dye and preparation method of mascara 浙江材华科技有限公司 2024-02-09 CN claimed
WO-2024019959-A1 COMPOSITIONS FOR MODULATING LIPOXYGENASE AND METHODS OF USING SAME THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2024-01-25 WO claimed
CN-117069676-A 6-methoxybenzothiazole compound and preparation method and application thereof 北京中医药大学 2023-11-17 CN claimed
EP-3054936-B1 4-((2-HYDROXY-3-METHOXYBENZYL)AMINO) BENZENESULFONAMIDE DERIVATIVES AS 12-LIPOXYGENASE INHIBITORS EASTERN VIRGINIA MEDICAL SCHOOL (US) 2023-10-18 EP claimed
WO-2011050198-A1 DISUBSTITUTED OCTAHY - DROPYRROLO [3,4-C] PYRROLES AS OREXIN RECEPTOR MODULATORS JANSSEN PHARMACEUTICA NV (BE) 2011-04-28 WO claimed
EP-0368327-B1 Light-sensitive composition FUJI PHOTO FILM CO LTD (JP) 1995-02-15 EP claimed
EP-0271260-B1 Supersensitization of silver halide emulsions MINNESOTA MINING & MFG (US) 1995-01-04 EP claimed
US-5202221-A Photocrosslinkable copolymer having maleimido side chain, cyanine dye sensitizer FUJI PHOTO FILM CO., LTD. (JP) 1993-04-13 US claimed
EP-0368327-A2 Light-sensitive composition FUJI PHOTO FILM CO., LTD. (JP) 1990-05-16 EP claimed
US-4891305-A LASERS RICOH CO., LTD. (JP) 1990-01-02 US claimed
US-4889796-A CONTAINING BENZOXAZOLE COMPOUND FUJI PHOTO FILM CO., LTD. (JP) 1989-12-26 US claimed
US-4873184-A ADDITION OF A METAL COMPLEXING AGENT TO THE EMULSION; HIGH SPEED MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1989-10-10 US claimed
EP-0271260-A2 Supersensitization of silver halide emulsions MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1988-06-15 EP claimed
US-3970461-A Fogged, direct-positive silver halide emulsion containing carbocyanine dye having indolenine nucleus FUJI PHOTO FILM CO., LTD. (JA) 1976-07-20 US claimed