Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 6/20 | 0.49 |
| ▸ | RAB9A | P51151 | 6/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | MEN1 | O00255 | 5/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 6/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | PFKFB3 | Q16875 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23133 | 0.85 | NPC1 (0.57) | NPC1RAB9AALDH1A1MEN1KMT2A | |
| Bromide SCHEMBL1193036 | 0.83 | NPC1 (0.56) | NPC1RAB9AALDH1A1MEN1KMT2A | |
| Toluene SCHEMBL11239856 | 0.78 | ALDH1A1 (0.49) | NPC1RAB9AALDH1A1MEN1KMT2A | |
| Benzo[D]Thiazole SCHEMBL360258 | 0.77 | ALDH1A1 (0.66) | NPC1RAB9AALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL29992983 | 0.73 | NPC1 (0.56) | NPC1RAB9AALDH1A1MEN1KMT2A | |
| SCHEMBL11719234 | 0.73 | RIPK2 (0.47) | NPC1RAB9AALDH1A1MEN1KMT2A | |
| SCHEMBL29967146 | 0.72 | NPC1 (0.47) | NPC1RAB9AALDH1A1MEN1KMT2A | |
| SCHEMBL928266 | 0.72 | NPC1 (0.47) | NPC1RAB9AALDH1A1MEN1KMT2A | |
| SCHEMBL8433660 | 0.71 | MEN1 (0.46) | NPC1RAB9AALDH1A1MEN1KMT2A | |
| SCHEMBL6032519 | 0.70 | RAB9A (0.46) | NPC1RAB9AALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012007510-A1 | COMPOUNDS FOR BINDING AND IMAGING AMYLOID PLAQUES AND THEIR USE | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2012-01-19 | — | — | WO | disclosed |