Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPEPPS | P55786 | 3/20 | 0.33 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.30 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.30 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.30 |
| ▸ | JAK3 | P52333 | 1/20 | 0.30 |
| ▸ | KLK7 | P49862 | 2/20 | 0.30 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25047765 | 0.84 | PRMT5 (0.33) | PRMT5WDR77JAK3 | |
| SCHEMBL25047420 | 0.82 | PRMT5 (0.34) | PRMT5WDR77JAK3 | |
| SCHEMBL29743109 | 0.82 | PRMT5 (0.34) | PRMT5WDR77JAK3 | |
| SCHEMBL23137092 | 0.81 | KLK7 (0.32) | NPEPPSKLK7KLK5 | |
| SCHEMBL23137075 | 0.79 | NPEPPS (0.30) | NPEPPS | |
| SCHEMBL29743106 | 0.78 | PRMT5 (0.31) | PRMT5WDR77 | |
| SCHEMBL23120444 | 0.78 | NPEPPS (0.30) | NPEPPS | |
| SCHEMBL25048314 | 0.78 | CPB2 (0.32) | PRMT5WDR77 | |
| SCHEMBL23120243 | 0.77 | NPEPPS (0.32) | NPEPPSKLK7KLK5 | |
| SCHEMBL23120248 | 0.77 | NPEPPS (0.32) | NPEPPSKLK7KLK5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021053158-A1 | NOVEL HISTONE METHYLTRANSFERASE INHIBITORS | ALBERT-LUDWIGS-UNIVERSITÄT FREIBURG (DE) | 2021-03-25 | — | — | WO | disclosed |