Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 10/20 | 0.34 |
| ▸ | WDR77 | Q9BQA1 | 7/20 | 0.34 |
| ▸ | JAK3 | P52333 | 2/20 | 0.33 |
| ▸ | JAK1 | P23458 | 3/20 | 0.33 |
| ▸ | NNMT | P40261 | 2/20 | 0.32 |
| ▸ | METTL3 | Q86U44 | 2/20 | 0.32 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.32 |
| ▸ | JAK2 | O60674 | 1/20 | 0.32 |
| ▸ | UBA6 | A0AVT1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29743109 | 1.00 | PRMT5 (0.34) | PRMT5WDR77JAK3JAK1NNMT | |
| SCHEMBL23120206 | 0.89 | PRMT5 (0.35) | PRMT5WDR77NNMTMETTL3DOT1L | |
| SCHEMBL29743106 | 0.88 | PRMT5 (0.31) | PRMT5WDR77 | |
| SCHEMBL25047765 | 0.88 | PRMT5 (0.33) | PRMT5WDR77JAK3 | |
| SCHEMBL20049564 | 0.86 | PDPK1 (0.34) | PRMT5WDR77JAK3JAK1NNMT | |
| SCHEMBL25046560 | 0.83 | ADK (0.41) | PRMT5WDR77DOT1L | |
| SCHEMBL23135872 | 0.82 | NPEPPS (0.33) | PRMT5WDR77JAK3 | |
| SCHEMBL9287692 | 0.78 | ADK (0.46) | PRMT5WDR77METTL3 | |
| SCHEMBL25047421 | 0.77 | JAK1 (0.38) | PRMT5WDR77JAK3JAK1JAK2 | |
| SCHEMBL23776516 | 0.77 | NNMT (0.39) | PRMT5WDR77NNMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023017152-A1 | SPECIFIC SMALL MOLECULE INHIBITORS THAT BLOCK KMT9 METHYLTRANSFERASE ACTIVITY AND FUNCTION | ALBERT-LUDWIGS-UNIVERSITÄT FREIBURG (DE) | 2023-02-16 | — | — | WO | disclosed |