Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23148856 | 0.84 | POLB (0.33) | POLB | |
| SCHEMBL28542561 | 0.79 | GAA (0.45) | RECQLGAAMEN1KMT2AEPHX1 | |
| SCHEMBL23148847 | 0.79 | RECQL (0.42) | RECQLGAAPOLBALDH1A1NPSR1 | |
| SCHEMBL23148795 | 0.71 | ALDH1A1 (0.35) | RECQLGAAALDH1A1NPSR1MEN1 | |
| SCHEMBL23148614 | 0.69 | RECQL (0.33) | RECQLNPC1RAB9A | |
| SCHEMBL28545503 | 0.69 | CTSK (0.51) | GAAMEN1KMT2A | |
| SCHEMBL23148736 | 0.68 | RECQL (0.32) | RECQLNPC1RAB9A | |
| SCHEMBL23148670 | 0.68 | TP53 (0.43) | RECQLPOLBALDH1A1MEN1KMT2A | |
| SCHEMBL23148788 | 0.65 | ALDH1A1 (0.67) | GAAALDH1A1LMNANPC1RAB9A | |
| SCHEMBL23148678 | 0.63 | NPC1 (0.39) | GAAALDH1A1KMT2ALMNANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210094941-A1 | Antimalarial Hexahydropyrimidine Analogues | UCB Biopharma SRL (BE) | 2021-04-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210094941-A1 | Antimalarial Hexahydropyrimidine Analogues | G6PD, DPYD, DHODH | RECQL 3027/4885GAA 3464/4885POLB 711/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.