Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K12 | Q12852 | 3/20 | 0.34 |
| ▸ | KDM5A | P29375 | 1/20 | 0.33 |
| ▸ | MGLL | Q99685 | 10/20 | 0.32 |
| ▸ | FAAH | O00519 | 7/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18423479 | 1.00 | MAP3K12 (0.34) | MAP3K12KDM5AMGLLFAAHCNR1 | |
| SCHEMBL23149395 | 1.00 | MAP3K12 (0.34) | MAP3K12KDM5AMGLLFAAHCNR1 | |
| SCHEMBL27148523 | 0.83 | MGLL (0.33) | MGLLFAAH | |
| SCHEMBL18418137 | 0.76 | — | — | |
| SCHEMBL18866160 | 0.75 | RAB9A (0.38) | KDM5A | |
| SCHEMBL21391903 | 0.74 | ALDH1A1 (0.38) | MGLLCNR1 | |
| SCHEMBL20585938 | 0.70 | MGLL (0.44) | MGLLFAAHCNR1 | |
| SCHEMBL20585941 | 0.70 | MGLL (0.44) | MGLLFAAHCNR1 | |
| SCHEMBL20585945 | 0.70 | MGLL (0.44) | MGLLFAAHCNR1 | |
| SCHEMBL30500991 | 0.70 | HDAC4 (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4028401-B1 | 4,4A,5,7,8,8A-HEXAPYRIDO[4,3-B][1,4]OXAZIN-3-ONE COMPOUNDS AS MAGL INHIBITORS | HOFFMANN LA ROCHE (CH) | 2023-11-22 | — | — | EP | disclosed |
| US-20210094971-A1 | HETEROCYCLIC COMPOUNDS | HOFFMANN-LA ROCHE INC. (US) | 2021-04-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210094971-A1 | HETEROCYCLIC COMPOUNDS | CYP1B1, CYP4B1, CYP4X1 | MAP3K12 3571/4885KDM5A 2130/4885MGLL 1712/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.