Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.43 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.43 |
| ▸ | CTSL | P07711 | 4/20 | 0.39 |
| ▸ | CTSB | P07858 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.38 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2315089 | 1.00 | PTGS2 (0.45) | PTGS2HDAC6HDAC1HDAC3HDAC4 | |
| Hydrochloric Acid SCHEMBL560376 | 0.99 | PTGS2 (0.44) | PTGS2HDAC6HDAC1HDAC3HDAC4 | |
| Hydrochloric Acid SCHEMBL560375 | 0.99 | PTGS2 (0.44) | PTGS2HDAC6HDAC1HDAC3HDAC4 | |
| SCHEMBL14401942 | 0.95 | PTGS2 (0.41) | PTGS2HDAC6HDAC1HDAC3HDAC4 | |
| SCHEMBL13327498 | 0.89 | HDAC3 (0.34) | PTGS2HDAC6HDAC1HDAC3HDAC4 | |
| SCHEMBL13327503 | 0.87 | HDAC3 (0.31) | PTGS2HDAC6HDAC1HDAC3HDAC4 | |
| SCHEMBL3823380 | 0.85 | WDR91 (0.35) | PTGS2HDAC6HDAC1HDAC3HDAC4 | |
| SCHEMBL3823383 | 0.85 | WDR91 (0.35) | PTGS2HDAC6HDAC1HDAC3HDAC4 | |
| Hydrochloric Acid SCHEMBL3386424 | 0.84 | WDR91 (0.34) | HDAC6HDAC1HDAC3HDAC4HDAC7 | |
| SCHEMBL10104223 | 0.84 | LMNA (0.33) | HDAC6HDAC1HDAC3HDAC4HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2677996-B1 | COMPOSITION FOR DYEING KERATINOUS FIBRES COMPRISING A DIRECT DYE HAVING A DISULPHIDE/THIOL FUNCTIONAL GROUP, A THICKENING POLYMER, AN ETHOXYLATED FATTY ALCOHOL AND/OR A NONIONIC SURFACTANT, AN ALKALINE AGENT AND A REDUCING AGENT | L'ORÉAL (FR) | 2017-11-29 | — | — | EP | disclosed |
| EP-2004758-B1 | DYEING COMPOSITION CONTAINING A THIOL/DISULPHIDE FLUORESCENT COLORANT COMPRISING A HETEROCYCLE, WITH AN INTERNAL CATIONIC CHARGE, AND METHOD FOR LIGHTENING KERATIN MATERIALS USING SAID COLORANT | OREAL (FR) | 2011-08-03 | — | — | EP | disclosed |
| EP-2004758-B1 | DYEING COMPOSITION CONTAINING A THIOL/DISULPHIDE FLUORESCENT COLORANT COMPRISING A HETEROCYCLE, WITH AN INTERNAL CATIONIC CHARGE, AND METHOD FOR LIGHTENING KERATIN MATERIALS USING SAID COLORANT | OREAL (FR) | 2011-08-03 | — | — | EP | disclosed |
| WO-2009109457-A2 | COMPOSITION FOR DYEING KERATIN FIBRES COMPRISING AT LEAST ONE DIRECT DYE COMPRISING A DISULPHIDE/PROTECTED-THIOL FUNCTION AND AT LEAST ONE SILICEOUS COMPOUND COMPRISING A THIOL FUNCTION AND METHOD USING THE COMPOSITION | L'OREAL (FR) | 2009-09-11 | — | — | WO | disclosed |
| WO-2007110539-A2 | DYEING COMPOSITION CONTAINING A THIOL/DISULPHIDE FLUORESCENT COLORANT COMPRISING A HETEROCYCLE, WITH AN INTERNAL CATIONIC CHARGE, AND METHOD FOR LIGHTENING KERATIN MATERIALS USING SAID COLORANT | L'ORÉAL (FR) | 2007-10-04 | — | — | WO | disclosed |