Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | RAD52 | P43351 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | GFER | P55789 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | RYR2 | Q92736 | 1/20 | 0.31 |
| ▸ | NPY1R | P25929 | 1/20 | 0.30 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.30 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10104559 | 0.91 | NPY1R (0.33) | KMT2ARAD52RXFP1KDM4EMAPT | |
| SCHEMBL2315084 | 0.84 | PTGS2 (0.45) | LMNAKMT2AKDM4EMAPTALDH1A1 | |
| SCHEMBL2315089 | 0.84 | PTGS2 (0.45) | LMNAKMT2AKDM4EMAPTALDH1A1 | |
| Hydrochloric Acid SCHEMBL560376 | 0.83 | PTGS2 (0.44) | LMNAKMT2AKDM4EMAPTALDH1A1 | |
| Hydrochloric Acid SCHEMBL560375 | 0.83 | PTGS2 (0.44) | LMNAKMT2AKDM4EMAPTALDH1A1 | |
| SCHEMBL10104165 | 0.81 | KMT2A (0.39) | LMNAGAAKMT2ARAD52RXFP1 | |
| SCHEMBL14401942 | 0.80 | PTGS2 (0.41) | LMNAKDM4EMAPTALDH1A1HDAC3 | |
| SCHEMBL14392874 | 0.80 | NPY1R (0.34) | KMT2ARAD52RXFP1KDM4EMAPT | |
| SCHEMBL10104252 | 0.78 | NPY1R (0.34) | GAAALDH1A1NPY1R | |
| SCHEMBL13294092 | 0.78 | NPY1R (0.32) | MAPK1KDM4EALDH1A1HPGDNPY1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140033450-A1 | METHOD OF DYEING AND LIGHTENING KERATIN MATERIALS IN THE PRESENCE OF A REDUCING AGENT COMPRISING A FLUORESCENT DEISULPHIDE DYE | L'OREAL (FR) | 2014-02-06 | — | — | US | disclosed |
| US-20130074276-A1 | METHOD OF DYEING AND LIGHTENING KERATIN MATERIALS IN THE PRESENCE OF A REDUCING AGENT COMPRISING A FLUORESCENT DISULPHIDE DYE | L'OREAL S.A. (FR) | 2013-03-28 | — | — | US | disclosed |
| US-8328880-B2 | Method of colouring and lightening keratin materials in the presence of a reducing agent comprising a fluorescent disulphide dye | L'OREAL (FR) | 2012-12-11 | — | — | US | disclosed |
| US-20120177587-A1 | METHOD OF COLOURING AND LIGHTENING KERATIN MATERIALS IN THE PRESENCE OF A REDUCING AGENT COMPRISING A FLUORESCENT DISULPHIDE DYE | L'ORéAL S.A. | 2012-07-12 | — | — | US | disclosed |
| US-8097044-B2 | Hair compositions comprising at least one disulfide direct dye and at least one alkaline hydroxide agent and simultaneous hair shaping and dyeing processes | L'OREAL S.A. (FR) | 2012-01-17 | — | — | US | disclosed |
| US-20090313769-A1 | METHOD OF DYEING AND LIGHTENING KERATIN MATERIALS IN THE PRESENCE OF A REDUCING AGENT COMPRISING A FLUORESCENT DISULPHIDE DYE | L'OREAL S.A. (FR) | 2009-12-24 | — | — | US | disclosed |
| US-20090126755-A1 | Hair compositions comprising at least one disulfide direct dye and at least one alkaline hydroxide agent and simultaneous hair shaping an dyeing processes | L'OREAL S.A. (FR) | 2009-05-21 | — | — | US | disclosed |
| WO-2007110541-A2 | DYEING COMPOSITION CONTAINING A THIOL/DISULPHIDE FLUORESCENT COLORANT COMPRISING A CONDENSED CYCLE, WITH AN INTERNAL CATIONIC CHARGE, AND METHOD FOR LIGHTENING KERATIN MATERIALS USING SAID COLORANT | L'OREAL (FR) | 2007-10-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120177587-A1 | METHOD OF COLOURING AND LIGHTENING KERATIN MATERIALS IN THE PRESENCE OF A REDUCING AGENT COMPRISING A FLUORESCENT DISULPHIDE DYE | KRT18, DSG1, KRTCAP2 | LMNA 538/4885MAPK1 4092/4885GAA 3058/4885 |
| US-20090126755-A1 | Hair compositions comprising at least one disulfide direct dye and at least one alkaline hydroxide agent and simultaneous hair shaping an dyeing processes | KRT18, DSG1, ALPG | LMNA 2360/4885MAPK1 1265/4885GAA 2864/4885 |
| US-20140033450-A1 | METHOD OF DYEING AND LIGHTENING KERATIN MATERIALS IN THE PRESENCE OF A REDUCING AGENT COMPRISING A FLUORESCENT DEISULPHIDE DYE | KRT18, DSG1, DSP | LMNA 525/4885MAPK1 4177/4885GAA 3212/4885 |
| US-20130074276-A1 | METHOD OF DYEING AND LIGHTENING KERATIN MATERIALS IN THE PRESENCE OF A REDUCING AGENT COMPRISING A FLUORESCENT DISULPHIDE DYE | KRT18, DSG1, KRTCAP2 | LMNA 533/4885MAPK1 4175/4885GAA 3066/4885 |
| US-20090313769-A1 | METHOD OF DYEING AND LIGHTENING KERATIN MATERIALS IN THE PRESENCE OF A REDUCING AGENT COMPRISING A FLUORESCENT DISULPHIDE DYE | KRT18, DSG1, KRTCAP2 | LMNA 533/4885MAPK1 4175/4885GAA 3066/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.