Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | ERN1 | O75460 | 2/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.41 |
| ▸ | HTR3B | O95264 | 1/20 | 0.41 |
| ▸ | HTR3A | P46098 | 1/20 | 0.41 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.41 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29935837 | 1.00 | LMNA (0.48) | LMNAL3MBTL1MCL1MEN1KMT2A | |
| SCHEMBL30251616 | 0.81 | ALDH1A1 (0.42) | LMNAL3MBTL1ERN1ALDH1A1KDM4E | |
| SCHEMBL28910001 | 0.81 | ALDH1A1 (0.42) | LMNAL3MBTL1ERN1ALDH1A1KDM4E | |
| SCHEMBL423891 | 0.79 | L3MBTL1 (0.71) | LMNAL3MBTL1MEN1KMT2APOLB | |
| SCHEMBL29935705 | 0.77 | CYP1A2 (0.63) | L3MBTL1MEN1KMT2APOLBERN1 | |
| SCHEMBL1914529 | 0.77 | CYP1A2 (0.63) | L3MBTL1MEN1KMT2APOLBERN1 | |
| SCHEMBL12990293 | 0.77 | CYP1A2 (0.40) | LMNAL3MBTL1MCL1MEN1KMT2A | |
| SCHEMBL19651360 | 0.77 | NPC1 (0.44) | LMNAMEN1KMT2APOLBERN1 | |
| SCHEMBL9361568 | 0.76 | MAPT (0.66) | LMNAMEN1KMT2APOLBALDH1A1 | |
| SCHEMBL19422787 | 0.76 | NPC1 (0.49) | LMNAL3MBTL1MEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112574175-B | Quinoline compound, preparation method and application thereof | 南京长澳医药科技有限公司 | 2023-11-14 | — | — | CN | disclosed |
| WO-2021057190-A1 | QUINOLINE COMPOUNDS, PREPARATION METHOD THEREFOR AND USE THEREOF | 上海阳帆医药科技有限公司 | 2021-04-01 | — | — | WO | disclosed |
| CN-112574175-A | Quinoline compound, preparation method and application thereof | 上海阳帆医药科技有限公司 | 2021-03-30 | — | — | CN | disclosed |