Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.43 |
| ▸ | RELA | Q04206 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.41 |
| ▸ | ACR | P10323 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 6/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | RARB | P10826 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23153185 | 0.86 | LMNA (0.43) | NPC1LMNACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL21169020 | 0.86 | NPC1 (0.43) | NPC1LMNACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL25793413 | 0.86 | MAPT (0.47) | NPC1LMNACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL21560925 | 0.81 | RARB (0.59) | RARBHTTMAPK1POLB | |
| SCHEMBL21169022 | 0.80 | LMNA (0.38) | NPC1LMNACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL22621670 | 0.79 | NPC1 (0.39) | NPC1LMNACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL23153188 | 0.78 | PRSS1 (0.33) | NPC1LMNACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL25008908 | 0.78 | KCNH2 (0.46) | NPC1LMNACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL24778792 | 0.78 | MAPT (0.50) | LMNASMN1; SMN2PRSS1ACRMAPT | |
| SCHEMBL24969026 | 0.78 | MAPT (0.45) | LMNASMN1; SMN2PRSS1ACRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10961423-B2 | Curable composition, thermally conductive material, and device with thermally conductive layer | FUJIFILM CORPORATION (JP) | 2021-03-30 | — | — | US | disclosed |