Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.51 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | TTR | P02766 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | TERT | O14746 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 3/20 | 0.46 |
| ▸ | CA1 | P00915 | 3/20 | 0.46 |
| ▸ | CA2 | P00918 | 3/20 | 0.46 |
| ▸ | CA4 | P22748 | 3/20 | 0.46 |
| ▸ | CA9 | Q16790 | 3/20 | 0.46 |
| ▸ | NLN | Q9BYT8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23158643 | 0.84 | CTSL (0.57) | TERTMAPTSMN1; SMN2BCHEACHE | |
| SCHEMBL23158633 | 0.83 | TTR (0.58) | LMNAKMT2AUSP2TTRCYP2C9 | |
| SCHEMBL10801244 | 0.80 | TTR (0.59) | LMNAKMT2AUSP2TTRCYP2C9 | |
| SCHEMBL23158798 | 0.80 | TTR (0.54) | LMNAKMT2AUSP2TTRCYP2C9 | |
| SCHEMBL23158653 | 0.78 | TTR (0.53) | LMNAKMT2AUSP2TTRCYP2C9 | |
| Acetic Acid SCHEMBL10800042 | 0.78 | TTR (0.59) | LMNAKMT2AUSP2TTRCYP2C9 | |
| SCHEMBL23158582 | 0.77 | TTR (0.51) | LMNAKMT2AUSP2TTRCYP2C9 | |
| SCHEMBL23177650 | 0.76 | CXCL8 (0.52) | LMNAKMT2AUSP2TTRCYP2C9 | |
| SCHEMBL21401044 | 0.75 | CA12 (0.63) | LMNAKMT2AUSP2TTRCYP2C9 | |
| SCHEMBL8818066 | 0.75 | HDAC8 (0.60) | HDAC8LMNAKMT2ATERTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021060351-A1 | NSAID-BONDED ALGINIC ACID DERIVATIVE | 持田製薬株式会社 | 2021-04-01 | — | — | WO | disclosed |
| WO-2021060395-A1 | SUSTAINED-RELEASE PHARMACEUTICAL COMPOSITION | 持田製薬株式会社 | 2021-04-01 | — | — | WO | disclosed |